6TW8
Leishmania major N-myristoyltransferase in complex with indazole inhibitor IMP-917
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A [auth AAA] | NMT | e6tw8AAA2 | A: a+b three layers | X: Nat/Ivy | H: Acyl-CoA N-acyltransferases (Nat) (From Topology) | T: Acyl-CoA N-acyltransferases (Nat) | F: NMT | ECOD (1.6) |
A [auth AAA] | NMT_C | e6tw8AAA1 | A: a+b three layers | X: Nat/Ivy | H: Acyl-CoA N-acyltransferases (Nat) (From Topology) | T: Acyl-CoA N-acyltransferases (Nat) | F: NMT_C | ECOD (1.6) |
B [auth CCC] | NMT | e6tw8CCC2 | A: a+b three layers | X: Nat/Ivy | H: Acyl-CoA N-acyltransferases (Nat) (From Topology) | T: Acyl-CoA N-acyltransferases (Nat) | F: NMT | ECOD (1.6) |
B [auth CCC] | NMT_C | e6tw8CCC1 | A: a+b three layers | X: Nat/Ivy | H: Acyl-CoA N-acyltransferases (Nat) (From Topology) | T: Acyl-CoA N-acyltransferases (Nat) | F: NMT_C | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A [auth AAA], B [auth CCC] | PF01233 | Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain (NMT) | Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain | The N and C-terminal domains of NMT are structurally similar, each adopting an acyl-CoA N-acyltransferase-like fold. | Domain |
A [auth AAA], B [auth CCC] | PF02799 | Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain (NMT_C) | Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain | The N and C-terminal domains of NMT are structurally similar, each adopting an acyl-CoA N-acyltransferase-like fold. | Domain |