6SXF

Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with Tamoxifen (2.8 Angstrom resolution)

External Resource: Annotation


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AIon_transe6sxfA1 A: alpha complex topologyX: Voltage-gated ion channels (From Topology)H: Voltage-gated ion channels (From Topology)T: Voltage-gated ion channelsF: Ion_transECOD (1.6)
BIon_transe6sxfB1 A: alpha complex topologyX: Voltage-gated ion channels (From Topology)H: Voltage-gated ion channels (From Topology)T: Voltage-gated ion channelsF: Ion_transECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF08016Polycystin cation channel (PKD_channel)Polycystin cation channel- Family
A, B
PF00520Ion transport protein (Ion_trans)Ion transport protein- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
Ion transport protein -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B
IPR005821Ion transport domainDomain
A, B
IPR043203Voltage-gated cation channel calcium and sodiumFamily
A, B
IPR027359Voltage-dependent channel domain superfamilyHomologous Superfamily

Membrane Protein Annotation: OPM OPM Database Homepage

ChainsExternal LinkTypeClassSuperfamilyFamily
A, B
OPMTransmembraneAlpha-helical polytopicIon channel (VIC) superfamilyVoltage-gated calcium and sodium channels

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

ChainsExternal LinkComment
A, B
PDBTMAnnotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

ChainsExternal LinkComment
A, B
MemProtMDAnnotated as membrane protein by MemProtMD