6DXB
Crystal structure of chalcone synthase from Arabidopsis thaliana
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B [auth C] | d6dxbc1 | Alpha and beta proteins (a/b) | Thiolase-like | Thiolase-like | Chalcone synthase-like | automated matches | Mouse-ear cress (Arabidopsis thaliana ) [TaxId: 3702 ], | SCOPe (2.08) |
C [auth B] | d6dxbb1 | Alpha and beta proteins (a/b) | Thiolase-like | Thiolase-like | Chalcone synthase-like | automated matches | Mouse-ear cress (Arabidopsis thaliana ) [TaxId: 3702 ], | SCOPe (2.08) |
A | d6dxba1 | Alpha and beta proteins (a/b) | Thiolase-like | Thiolase-like | Chalcone synthase-like | automated matches | Mouse-ear cress (Arabidopsis thaliana ) [TaxId: 3702 ], | SCOPe (2.08) |
D | d6dxbd1 | Alpha and beta proteins (a/b) | Thiolase-like | Thiolase-like | Chalcone synthase-like | automated matches | Mouse-ear cress (Arabidopsis thaliana ) [TaxId: 3702 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B [auth C] | ACP_syn_III_C | e6dxbC1 | A: a/b three-layered sandwiches | X: Thiolase-like (From Topology) | H: Thiolase-like (From Topology) | T: Thiolase-like | F: ACP_syn_III_C | ECOD (1.6) |
B [auth C] | Chal_sti_synt_N | e6dxbC2 | A: a/b three-layered sandwiches | X: Thiolase-like (From Topology) | H: Thiolase-like (From Topology) | T: Thiolase-like | F: Chal_sti_synt_N | ECOD (1.6) |
C [auth B] | ACP_syn_III_C | e6dxbB2 | A: a/b three-layered sandwiches | X: Thiolase-like (From Topology) | H: Thiolase-like (From Topology) | T: Thiolase-like | F: ACP_syn_III_C | ECOD (1.6) |
C [auth B] | Chal_sti_synt_N | e6dxbB1 | A: a/b three-layered sandwiches | X: Thiolase-like (From Topology) | H: Thiolase-like (From Topology) | T: Thiolase-like | F: Chal_sti_synt_N | ECOD (1.6) |
A | ACP_syn_III_C | e6dxbA1 | A: a/b three-layered sandwiches | X: Thiolase-like (From Topology) | H: Thiolase-like (From Topology) | T: Thiolase-like | F: ACP_syn_III_C | ECOD (1.6) |
A | Chal_sti_synt_N | e6dxbA2 | A: a/b three-layered sandwiches | X: Thiolase-like (From Topology) | H: Thiolase-like (From Topology) | T: Thiolase-like | F: Chal_sti_synt_N | ECOD (1.6) |
D | ACP_syn_III_C | e6dxbD2 | A: a/b three-layered sandwiches | X: Thiolase-like (From Topology) | H: Thiolase-like (From Topology) | T: Thiolase-like | F: ACP_syn_III_C | ECOD (1.6) |
D | Chal_sti_synt_N | e6dxbD1 | A: a/b three-layered sandwiches | X: Thiolase-like (From Topology) | H: Thiolase-like (From Topology) | T: Thiolase-like | F: Chal_sti_synt_N | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B [auth C] | 3.40.47.10 | Alpha Beta | 3-Layer(aba) Sandwich | Peroxisomal Thiolase | Chain A, domain 1 | CATH (4.3.0) |
C [auth B] | 3.40.47.10 | Alpha Beta | 3-Layer(aba) Sandwich | Peroxisomal Thiolase | Chain A, domain 1 | CATH (4.3.0) |
A | 3.40.47.10 | Alpha Beta | 3-Layer(aba) Sandwich | Peroxisomal Thiolase | Chain A, domain 1 | CATH (4.3.0) |
D | 3.40.47.10 | Alpha Beta | 3-Layer(aba) Sandwich | Peroxisomal Thiolase | Chain A, domain 1 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A, B [auth C], C [auth B], D | PF00195 | Chalcone and stilbene synthases, N-terminal domain (Chal_sti_synt_N) | Chalcone and stilbene synthases, N-terminal domain | The C-terminal domain of Chalcone synthase is reported to be structurally similar to domains in thiolase and beta-ketoacyl synthase. The differences in activity are accounted for by differences in this N-terminal domain. | Domain |
A, B [auth C], C [auth B], D | PF02797 | Chalcone and stilbene synthases, C-terminal domain (Chal_sti_synt_C) | Chalcone and stilbene synthases, C-terminal domain | This domain of chalcone synthase is reported to be structurally similar to domains in thiolase and beta-ketoacyl synthase. The differences in activity are accounted for by differences in the N-terminal domain. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
A, B [auth C], C [auth B], D | IPR001099 | Chalcone/stilbene synthase, N-terminal | Domain |
A, B [auth C], C [auth B], D | IPR016039 | Thiolase-like | Homologous Superfamily |
A, B [auth C], C [auth B], D | IPR012328 | Chalcone/stilbene synthase, C-terminal | Domain |
A, B [auth C], C [auth B], D | IPR011141 | Polyketide synthase, type III | Family |
A, B [auth C], C [auth B], D | IPR018088 | Chalcone/stilbene synthase, active site | Active Site |
Protein Modification Annotation
Modified Residue(s) | ||
---|---|---|
Chain | Residue(s) | Description |
A, B [auth C], C [auth B], D | CSD | Parent Component: CYS :  AA0262 :  L-cysteine sulfinic acid MOD:00267 |