Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
B [auth A]SCOP2B SuperfamilyPhospholipase A2, PLA2 8062731 3001690 SCOP2B (2022-06-29)
A [auth B]SCOP2B SuperfamilyPhospholipase A2, PLA2 8062731 3001690 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
B [auth A]Phospholip_A2_1e6b83A1 A: few secondary structure elementsX: Phospholipase A2, PLA2 (From Topology)H: Phospholipase A2, PLA2 (From Topology)T: Phospholipase A2, PLA2F: Phospholip_A2_1ECOD (1.6)
A [auth B]Phospholip_A2_1e6b83B1 A: few secondary structure elementsX: Phospholipase A2, PLA2 (From Topology)H: Phospholipase A2, PLA2 (From Topology)T: Phospholipase A2, PLA2F: Phospholip_A2_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
B [auth A]1.20.90.10 Mainly Alpha Up-down Bundle Phospholipase A2 Phospholipase A2 domainCATH (4.3.0)
A [auth B]1.20.90.10 Mainly Alpha Up-down Bundle Phospholipase A2 Phospholipase A2 domainCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth B],
B [auth A]
PF00068Phospholipase A2 (Phospholip_A2_1)Phospholipase A2Phospholipase A2 releases fatty acids from the second carbon group of glycerol. Perhaps the best known members are secreted snake venoms, but also found in secreted pancreatic and membrane-associated forms. Structure is all-alpha, with two core disul ...Phospholipase A2 releases fatty acids from the second carbon group of glycerol. Perhaps the best known members are secreted snake venoms, but also found in secreted pancreatic and membrane-associated forms. Structure is all-alpha, with two core disulfide-linked helices and a calcium-binding loop. This alignment represents the major family of PLA2s. A second minor family, defined by the honeybee venom PLA2 PDB:1POC and related sequences from Gila monsters (Heloderma), is not recognised. This minor family conserves the core helix pair but is substantially different elsewhere. The PROSITE pattern PA2_HIS, specific to the first core helix, recognises both families.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth B],
B [auth A]
Basic phospholipase A2 homolog 2