5L3K

Structure of Mycobacterium thermoresistibile trehalose-6-phosphate synthase in a ternary complex with ADP and fructose-6-phosphate

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d5l3kb_	Alpha and beta proteins (a/b)	UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	automated matches	automated matches	(Mycolicibacterium thermoresistibile ) [TaxId: 1797 ],	SCOPe (2.08)
C	d5l3kc_	Alpha and beta proteins (a/b)	UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	automated matches	automated matches	(Mycolicibacterium thermoresistibile ) [TaxId: 1797 ],	SCOPe (2.08)
E	d5l3ke_	Alpha and beta proteins (a/b)	UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	automated matches	automated matches	(Mycolicibacterium thermoresistibile ) [TaxId: 1797 ],	SCOPe (2.08)
A	d5l3ka_	Alpha and beta proteins (a/b)	UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	automated matches	automated matches	(Mycolicibacterium thermoresistibile ) [TaxId: 1797 ],	SCOPe (2.08)
D	d5l3kd_	Alpha and beta proteins (a/b)	UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	automated matches	automated matches	(Mycolicibacterium thermoresistibile ) [TaxId: 1797 ],	SCOPe (2.08)
F	d5l3kf_	Alpha and beta proteins (a/b)	UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	automated matches	automated matches	(Mycolicibacterium thermoresistibile ) [TaxId: 1797 ],	SCOPe (2.08)
G	d5l3kg_	Alpha and beta proteins (a/b)	UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	automated matches	automated matches	(Mycolicibacterium thermoresistibile ) [TaxId: 1797 ],	SCOPe (2.08)
H	d5l3kh_	Alpha and beta proteins (a/b)	UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	automated matches	automated matches	(Mycolicibacterium thermoresistibile ) [TaxId: 1797 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	Type B glycosyltransferase-like	8079968	3001586	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Type B glycosyltransferase-like	8079968	3001586	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Type B glycosyltransferase-like	8079968	3001586	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Type B glycosyltransferase-like	8079968	3001586	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Type B glycosyltransferase-like	8079968	3001586	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Type B glycosyltransferase-like	8079968	3001586	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Type B glycosyltransferase-like	8079968	3001586	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Type B glycosyltransferase-like	8079968	3001586	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	Glyco_transf_20_N	e5l3kB2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_20_N	ECOD (1.6)
B	Glyco_transf_20_C	e5l3kB1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_20_C	ECOD (1.6)
C	Glyco_transf_20_N	e5l3kC1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_20_N	ECOD (1.6)
C	Glyco_transf_20_C	e5l3kC2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_20_C	ECOD (1.6)
E	Glyco_transf_20_N	e5l3kE2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_20_N	ECOD (1.6)
E	Glyco_transf_20_C	e5l3kE1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_20_C	ECOD (1.6)
A	Glyco_transf_20_N	e5l3kA2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_20_N	ECOD (1.6)
A	Glyco_transf_20_C	e5l3kA1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_20_C	ECOD (1.6)
D	Glyco_transf_20_N	e5l3kD1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_20_N	ECOD (1.6)
D	Glyco_transf_20_C	e5l3kD2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_20_C	ECOD (1.6)
F	Glyco_transf_20_N	e5l3kF2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_20_N	ECOD (1.6)
F	Glyco_transf_20_C	e5l3kF1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_20_C	ECOD (1.6)
G	Glyco_transf_20_N	e5l3kG2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_20_N	ECOD (1.6)
G	Glyco_transf_20_C	e5l3kG1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_20_C	ECOD (1.6)
H	Glyco_transf_20_N	e5l3kH1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_20_N	ECOD (1.6)
H	Glyco_transf_20_C	e5l3kH2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_20_C	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
C	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
E	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
A	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
D	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
F	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
G	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
H	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF00982	Glycosyltransferase family 20 (Glyco_transf_20)	Glycosyltransferase family 20	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	Alpha,alpha-trehalose-phosphate synthase	glycosyltransferase activity transferase activity hexosyltransferase activity catalytic activity binding nucleoside phosphate binding organic cyclic compound binding nucleotide binding heterocyclic compound binding small molecule binding	carbohydrate metabolic process trehalose metabolic process carbohydrate biosynthetic process oligosaccharide metabolic process primary metabolic process disaccharide metabolic process disaccharide biosynthetic process biosynthetic process oligosaccharide biosynthetic process trehalose biosynthetic process metabolic process cellular process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR001830	Glycosyl transferase, family 20	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.