4ORO

Structure of Influenza B PB2 cap-binding domain complex with GDP

External Resource: Annotation


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad4oroa1 Alpha and beta proteins (a+b) Influenza virus PB2 cap binding domain-like Influenza virus PB2 cap binding domain-like automated matches automated matches (Influenza B virus ) [TaxId: 11520 ], SCOPe (2.08)
Ad4oroa2 Artifacts Tags Tags Tags N-terminal Tags (Influenza B virus ) [TaxId: 11520 ], SCOPe (2.08)
Cd4oroc1 Alpha and beta proteins (a+b) Influenza virus PB2 cap binding domain-like Influenza virus PB2 cap binding domain-like automated matches automated matches (Influenza B virus ) [TaxId: 11520 ], SCOPe (2.08)
Cd4oroc2 Artifacts Tags Tags Tags N-terminal Tags (Influenza B virus ) [TaxId: 11520 ], SCOPe (2.08)
Dd4orod1 Alpha and beta proteins (a+b) Influenza virus PB2 cap binding domain-like Influenza virus PB2 cap binding domain-like automated matches automated matches (Influenza B virus ) [TaxId: 11520 ], SCOPe (2.08)
Dd4orod2 Artifacts Tags Tags Tags N-terminal Tags (Influenza B virus ) [TaxId: 11520 ], SCOPe (2.08)
Bd4orob1 Alpha and beta proteins (a+b) Influenza virus PB2 cap binding domain-like Influenza virus PB2 cap binding domain-like automated matches automated matches (Influenza B virus ) [TaxId: 11520 ], SCOPe (2.08)
Bd4orob2 Artifacts Tags Tags Tags N-terminal Tags (Influenza B virus ) [TaxId: 11520 ], SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AFlu_PB2_5the4oroA1 A: a+b three layersX: Polymerase basic protein 2 cap-binding domain (From Topology)H: Polymerase basic protein 2 cap-binding domain (From Topology)T: Polymerase basic protein 2 cap-binding domainF: Flu_PB2_5thECOD (1.6)
CFlu_PB2_5the4oroC1 A: a+b three layersX: Polymerase basic protein 2 cap-binding domain (From Topology)H: Polymerase basic protein 2 cap-binding domain (From Topology)T: Polymerase basic protein 2 cap-binding domainF: Flu_PB2_5thECOD (1.6)
DFlu_PB2_5the4oroD1 A: a+b three layersX: Polymerase basic protein 2 cap-binding domain (From Topology)H: Polymerase basic protein 2 cap-binding domain (From Topology)T: Polymerase basic protein 2 cap-binding domainF: Flu_PB2_5thECOD (1.6)
BFlu_PB2_5the4oroB1 A: a+b three layersX: Polymerase basic protein 2 cap-binding domain (From Topology)H: Polymerase basic protein 2 cap-binding domain (From Topology)T: Polymerase basic protein 2 cap-binding domainF: Flu_PB2_5thECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF00604Influenza RNA polymerase PB2 CAP binding domain (Flu_PB2_5th)Influenza RNA polymerase PB2 CAP binding domainInfluenza virus encodes a large, multidomain RNA-dependent RNA polymerase that can both transcribe and replicate the viral RNA genome. In influenza virus, the polymerase is composed of three polypeptides: PB1, PB2 and PA/P3. PB1 houses the polymerase ...Influenza virus encodes a large, multidomain RNA-dependent RNA polymerase that can both transcribe and replicate the viral RNA genome. In influenza virus, the polymerase is composed of three polypeptides: PB1, PB2 and PA/P3. PB1 houses the polymerase active site, whereas PB2 and PA/P3 contain, respectively, cap-binding [1] and endonuclease domains required for transcription initiation by cap-snatching [2]. This entry represents the CAP binding domain [2].
Domain

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D
IPR048298Influenza RNA polymerase PB2, CAP binding domainDomain