3SCM
Crystal structure of autoreactive-Valpha14-Vbeta6 NKT TCR in complex with CD1d-isoglobotrihexosylceramide
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B | SCOP2B Superfamily | Immunoglobulin (Ig) domain-like | 8054571 | 3000071 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Immunoglobulin (Ig) domain-like | 8054657 | 3000071 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | MHC antigen-recognition domain | 8037146 | 3000521 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | Immunoglobulin (Ig) domain-like | 8054547 | 3000071 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | C1-set_2 | e3scmB1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: C1-set_2 | ECOD (1.6) |
A | C1-set_2 | e3scmA1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: C1-set_2 | ECOD (1.6) |
A | MHC_I | e3scmA2 | A: a+b two layers | X: MHC antigen-recognition domain (From Topology) | H: MHC antigen-recognition domain (From Topology) | T: MHC antigen-recognition domain | F: MHC_I | ECOD (1.6) |
C | DUF1968 | e3scmC3 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: DUF1968 | ECOD (1.6) |
C | V-set_4 | e3scmC4 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_4 | ECOD (1.6) |
D | C1-set | e3scmD2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: C1-set | ECOD (1.6) |
D | V-set_3 | e3scmD1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_3 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 2.60.40.10 | Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulins | CATH (4.3.0) |
A | 3.30.500.10 | Alpha Beta | 2-Layer Sandwich | Murine Class I Major Histocompatibility Complex, H2-DB | Chain A, domain 1 | CATH (4.3.0) |
A | 2.60.40.10 | Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulins | CATH (4.3.0) |
C | 2.60.40.10 | Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulins | CATH (4.3.0) |
D | 2.60.40.10 | Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulins | CATH (4.3.0) |
IMGT Antibody Annotation IMGT Database Homepage
Chain | Protein Name | Description | Organism Name | Gene Allele Name(s) | Domain Name(s) | Receptor Type | Receptor Description | Provenance Source |
---|---|---|---|---|---|---|---|---|
CD1D1 | B2M | Mus musculus (house mouse) | B2M*01 | C-LIKE-DOMAIN C-LIKE | RPI-MH1Like | MH1LIKE-ALPHA-LIKE_B2M | IMGT (202447-0) | |
CD1D1 | I-ALPHA-LIKE | Mus musculus (house mouse) | - | - | RPI-MH1Like | MH1LIKE-ALPHA-LIKE_B2M | IMGT (202447-0) | |
TR TRAV11*02-TRAJ18*01, TRBV19*01 | TR-ALPHA | Chimeric (chimeric) | TRAV11*02, TRAJ18*01, TRAC*01 | V-DOMAIN V-ALPHA, C-DOMAIN C-ALPHA | TR | TR-ALPHA_BETA-2 | IMGT (202447-0) | |
TR TRAV11*02-TRAJ18*01, TRBV19*01 | TR-BETA-2 | Chimeric (chimeric) | TRBV19*01, TRBJ1-1*01, TRBC2*01, TRBC2*02 | V-DOMAIN V-BETA, C-DOMAIN C-BETA-2 | TR | TR-ALPHA_BETA-2 | IMGT (202447-0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF07654 | Immunoglobulin C1-set domain (C1-set) | Immunoglobulin C1-set domain | - | Domain | |
PF07654 | Immunoglobulin C1-set domain (C1-set) | Immunoglobulin C1-set domain | - | Domain | |
PF09291 | Domain of unknown function (DUF1968) (DUF1968) | Domain of unknown function (DUF1968) | Members of this family are found in mammalian T-cell antigen receptor, and adopt an immunoglobulin-like beta-sandwich fold, with seven strands in two beta-sheets in a Greek-key topology. Their exact function has not, as yet, been determined. | Domain | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target   | Associated Disease |
---|---|---|
P01848 | :