Annotations: 2IGK

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	pyranose_ox	e2igkB5	A: a+b two layers	X: FAD-linked reductases, C-terminal domain-like	H: FAD-linked reductases-C (From Topology)	T: FAD-linked reductases-C	F: pyranose_ox	ECOD (1.6)
B	GMC_oxred_N	e2igkB6	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: GMC_oxred_N	ECOD (1.6)
C	pyranose_ox	e2igkC5	A: a+b two layers	X: FAD-linked reductases, C-terminal domain-like	H: FAD-linked reductases-C (From Topology)	T: FAD-linked reductases-C	F: pyranose_ox	ECOD (1.6)
C	GMC_oxred_N	e2igkC6	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: GMC_oxred_N	ECOD (1.6)
E	pyranose_ox	e2igkE5	A: a+b two layers	X: FAD-linked reductases, C-terminal domain-like	H: FAD-linked reductases-C (From Topology)	T: FAD-linked reductases-C	F: pyranose_ox	ECOD (1.6)
E	GMC_oxred_N	e2igkE6	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: GMC_oxred_N	ECOD (1.6)
F	pyranose_ox	e2igkF5	A: a+b two layers	X: FAD-linked reductases, C-terminal domain-like	H: FAD-linked reductases-C (From Topology)	T: FAD-linked reductases-C	F: pyranose_ox	ECOD (1.6)
F	GMC_oxred_N	e2igkF6	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: GMC_oxred_N	ECOD (1.6)
G	pyranose_ox	e2igkG5	A: a+b two layers	X: FAD-linked reductases, C-terminal domain-like	H: FAD-linked reductases-C (From Topology)	T: FAD-linked reductases-C	F: pyranose_ox	ECOD (1.6)
G	GMC_oxred_N	e2igkG6	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: GMC_oxred_N	ECOD (1.6)
A	pyranose_ox	e2igkA5	A: a+b two layers	X: FAD-linked reductases, C-terminal domain-like	H: FAD-linked reductases-C (From Topology)	T: FAD-linked reductases-C	F: pyranose_ox	ECOD (1.6)
A	GMC_oxred_N	e2igkA6	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: GMC_oxred_N	ECOD (1.6)
D	pyranose_ox	e2igkD5	A: a+b two layers	X: FAD-linked reductases, C-terminal domain-like	H: FAD-linked reductases-C (From Topology)	T: FAD-linked reductases-C	F: pyranose_ox	ECOD (1.6)
D	GMC_oxred_N	e2igkD6	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: GMC_oxred_N	ECOD (1.6)
H	pyranose_ox	e2igkH5	A: a+b two layers	X: FAD-linked reductases, C-terminal domain-like	H: FAD-linked reductases-C (From Topology)	T: FAD-linked reductases-C	F: pyranose_ox	ECOD (1.6)
H	GMC_oxred_N	e2igkH6	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: GMC_oxred_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.30.1920.50	Alpha Beta	2-Layer Sandwich	Phage tail proteins - 2 layer sandwich fold		CATH (4.3.0)
C	3.30.1920.50	Alpha Beta	2-Layer Sandwich	Phage tail proteins - 2 layer sandwich fold		CATH (4.3.0)
E	3.30.1920.50	Alpha Beta	2-Layer Sandwich	Phage tail proteins - 2 layer sandwich fold		CATH (4.3.0)
F	3.30.1920.50	Alpha Beta	2-Layer Sandwich	Phage tail proteins - 2 layer sandwich fold		CATH (4.3.0)
G	3.30.1920.50	Alpha Beta	2-Layer Sandwich	Phage tail proteins - 2 layer sandwich fold		CATH (4.3.0)
A	3.30.1920.50	Alpha Beta	2-Layer Sandwich	Phage tail proteins - 2 layer sandwich fold		CATH (4.3.0)
D	3.30.1920.50	Alpha Beta	2-Layer Sandwich	Phage tail proteins - 2 layer sandwich fold		CATH (4.3.0)
H	3.30.1920.50	Alpha Beta	2-Layer Sandwich	Phage tail proteins - 2 layer sandwich fold		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF05199	GMC oxidoreductase (GMC_oxred_C)	GMC oxidoreductase	This domain found associated with Pfam:PF00732.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	Pyranose oxidase	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor oxidoreductase activity oxidoreductase activity, acting on CH-OH group of donors pyranose oxidase activity catalytic activity flavin adenine dinucleotide binding binding nucleoside phosphate binding ion binding organic cyclic compound binding anion binding nucleotide binding heterocyclic compound binding small molecule binding	-	cellular anatomical structure periplasmic space

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR012814	Pyranose 2-oxidase	Family
A, B, C, D, E A, B, C, D, E, F, G, H	IPR007867	Glucose-methanol-choline oxidoreductase, C-terminal	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR036188	FAD/NAD(P)-binding domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H	IPR051473	Pyranose 2-oxidase-like	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.