Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad1yq2a1 All beta proteins Immunoglobulin-like beta-sandwich beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain beta-Galactosidase, domains 2 and 4 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Ad1yq2a3 All beta proteins Galactose-binding domain-like Galactose-binding domain-like beta-Galactosidase/glucuronidase, N-terminal domain beta-Galactosidase (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Ad1yq2a4 All beta proteins Supersandwich Galactose mutarotase-like beta-Galactosidase, domain 5 beta-Galactosidase, domain 5 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Ad1yq2a5 Alpha and beta proteins (a/b) TIM beta/alpha-barrel (Trans)glycosidases beta-glycanases beta-Galactosidase, domain 3 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Bd1yq2b1 All beta proteins Immunoglobulin-like beta-sandwich beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain beta-Galactosidase, domains 2 and 4 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Bd1yq2b3 All beta proteins Galactose-binding domain-like Galactose-binding domain-like beta-Galactosidase/glucuronidase, N-terminal domain beta-Galactosidase (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Bd1yq2b4 All beta proteins Supersandwich Galactose mutarotase-like beta-Galactosidase, domain 5 beta-Galactosidase, domain 5 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Bd1yq2b5 Alpha and beta proteins (a/b) TIM beta/alpha-barrel (Trans)glycosidases beta-glycanases beta-Galactosidase, domain 3 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Cd1yq2c1 All beta proteins Immunoglobulin-like beta-sandwich beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain beta-Galactosidase, domains 2 and 4 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Cd1yq2c3 All beta proteins Galactose-binding domain-like Galactose-binding domain-like beta-Galactosidase/glucuronidase, N-terminal domain beta-Galactosidase (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Cd1yq2c4 All beta proteins Supersandwich Galactose mutarotase-like beta-Galactosidase, domain 5 beta-Galactosidase, domain 5 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Cd1yq2c5 Alpha and beta proteins (a/b) TIM beta/alpha-barrel (Trans)glycosidases beta-glycanases beta-Galactosidase, domain 3 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Ed1yq2e1 All beta proteins Immunoglobulin-like beta-sandwich beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain beta-Galactosidase, domains 2 and 4 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Ed1yq2e3 All beta proteins Galactose-binding domain-like Galactose-binding domain-like beta-Galactosidase/glucuronidase, N-terminal domain beta-Galactosidase (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Ed1yq2e4 All beta proteins Supersandwich Galactose mutarotase-like beta-Galactosidase, domain 5 beta-Galactosidase, domain 5 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Ed1yq2e5 Alpha and beta proteins (a/b) TIM beta/alpha-barrel (Trans)glycosidases beta-glycanases beta-Galactosidase, domain 3 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Fd1yq2f1 All beta proteins Immunoglobulin-like beta-sandwich beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain beta-Galactosidase, domains 2 and 4 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Fd1yq2f3 All beta proteins Galactose-binding domain-like Galactose-binding domain-like beta-Galactosidase/glucuronidase, N-terminal domain beta-Galactosidase (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Fd1yq2f4 All beta proteins Supersandwich Galactose mutarotase-like beta-Galactosidase, domain 5 beta-Galactosidase, domain 5 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Fd1yq2f5 Alpha and beta proteins (a/b) TIM beta/alpha-barrel (Trans)glycosidases beta-glycanases beta-Galactosidase, domain 3 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Dd1yq2d1 All beta proteins Immunoglobulin-like beta-sandwich beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain beta-Galactosidase, domains 2 and 4 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Dd1yq2d3 All beta proteins Galactose-binding domain-like Galactose-binding domain-like beta-Galactosidase/glucuronidase, N-terminal domain beta-Galactosidase (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Dd1yq2d4 All beta proteins Supersandwich Galactose mutarotase-like beta-Galactosidase, domain 5 beta-Galactosidase, domain 5 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)
Dd1yq2d5 Alpha and beta proteins (a/b) TIM beta/alpha-barrel (Trans)glycosidases beta-glycanases beta-Galactosidase, domain 3 (Arthrobacter sp. C2-2 ) [TaxId: 192168 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 Familybeta-Galactosidase N-terminal domain-like 8022457 4002476 SCOP2 (2022-06-29)
ASCOP2 Familybeta-galactosidase, domain 5 8022458 4002767 SCOP2 (2022-06-29)
ASCOP2 Familybeta-glycanases 8022459 4003164 SCOP2 (2022-06-29)
ASCOP2 Familybeta-Galactosidase/glucuronidase domain 8055210 4007531 SCOP2 (2022-06-29)
ASCOP2 Familybeta-Galactosidase/glucuronidase domain 8055463 4007531 SCOP2 (2022-06-29)
ASCOP2 Superfamilygalactose-binding domain-like 8034837 3000087 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyGalactose mutarotase-like 8034838 3000035 SCOP2 (2022-06-29)
ASCOP2 Superfamily(Trans)glycosidases 8034839 3000313 SCOP2 (2022-06-29)
ASCOP2 Superfamilybeta-Galactosidase/glucuronidase domain-like 8055211 3002047 SCOP2 (2022-06-29)
ASCOP2 Superfamilybeta-Galactosidase/glucuronidase domain-like 8055464 3002047 SCOP2 (2022-06-29)
BSCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055211 3002047 SCOP2B (2022-06-29)
BSCOP2B Superfamilygalactose-binding domain-like 8034837 3000087 SCOP2B (2022-06-29)
BSCOP2B Superfamily(Trans)glycosidases 8034839 3000313 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyGalactose mutarotase-like 8034838 3000035 SCOP2B (2022-06-29)
BSCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055464 3002047 SCOP2B (2022-06-29)
CSCOP2B Superfamily(Trans)glycosidases 8034839 3000313 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyGalactose mutarotase-like 8034838 3000035 SCOP2B (2022-06-29)
CSCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055211 3002047 SCOP2B (2022-06-29)
CSCOP2B Superfamilygalactose-binding domain-like 8034837 3000087 SCOP2B (2022-06-29)
CSCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055464 3002047 SCOP2B (2022-06-29)
ESCOP2B Superfamily(Trans)glycosidases 8034839 3000313 SCOP2B (2022-06-29)
ESCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055211 3002047 SCOP2B (2022-06-29)
ESCOP2B Superfamilygalactose-binding domain-like 8034837 3000087 SCOP2B (2022-06-29)
ESCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055464 3002047 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyGalactose mutarotase-like 8034838 3000035 SCOP2B (2022-06-29)
FSCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055464 3002047 SCOP2B (2022-06-29)
FSCOP2B Superfamilygalactose-binding domain-like 8034837 3000087 SCOP2B (2022-06-29)
FSCOP2B Superfamily(Trans)glycosidases 8034839 3000313 SCOP2B (2022-06-29)
FSCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055211 3002047 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyGalactose mutarotase-like 8034838 3000035 SCOP2B (2022-06-29)
DSCOP2B Superfamily(Trans)glycosidases 8034839 3000313 SCOP2B (2022-06-29)
DSCOP2B Superfamilygalactose-binding domain-like 8034837 3000087 SCOP2B (2022-06-29)
DSCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055211 3002047 SCOP2B (2022-06-29)
DSCOP2B Superfamilybeta-Galactosidase/glucuronidase domain-like 8055464 3002047 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyGalactose mutarotase-like 8034838 3000035 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AGlyco_hydro_2_Ne1yq2A1 A: beta sandwichesX: jelly-rollH: Concanavalin A-likeT: Galactose-binding domain-likeF: Glyco_hydro_2_NECOD (1.6)
AGlyco_hydro_2e1yq2A3 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: Glyco_hydro_2ECOD (1.6)
ADUF4981e1yq2A2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF4981ECOD (1.6)
ABgal_small_Ne1yq2A4 A: beta sandwichesX: Glycosyl hydrolase domain-likeH: supersandwich (From Topology)T: supersandwichF: Bgal_small_NECOD (1.6)
AGlyco_hydro_2_Ce1yq2A5 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Glyco_hydro_2_CECOD (1.6)
BGlyco_hydro_2_Ne1yq2B1 A: beta sandwichesX: jelly-rollH: Concanavalin A-likeT: Galactose-binding domain-likeF: Glyco_hydro_2_NECOD (1.6)
BGlyco_hydro_2e1yq2B3 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: Glyco_hydro_2ECOD (1.6)
BDUF4981e1yq2B2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF4981ECOD (1.6)
BBgal_small_Ne1yq2B4 A: beta sandwichesX: Glycosyl hydrolase domain-likeH: supersandwich (From Topology)T: supersandwichF: Bgal_small_NECOD (1.6)
BGlyco_hydro_2_Ce1yq2B5 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Glyco_hydro_2_CECOD (1.6)
CGlyco_hydro_2_Ne1yq2C1 A: beta sandwichesX: jelly-rollH: Concanavalin A-likeT: Galactose-binding domain-likeF: Glyco_hydro_2_NECOD (1.6)
CGlyco_hydro_2e1yq2C3 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: Glyco_hydro_2ECOD (1.6)
CDUF4981e1yq2C2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF4981ECOD (1.6)
CBgal_small_Ne1yq2C4 A: beta sandwichesX: Glycosyl hydrolase domain-likeH: supersandwich (From Topology)T: supersandwichF: Bgal_small_NECOD (1.6)
CGlyco_hydro_2_Ce1yq2C5 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Glyco_hydro_2_CECOD (1.6)
EGlyco_hydro_2_Ne1yq2E1 A: beta sandwichesX: jelly-rollH: Concanavalin A-likeT: Galactose-binding domain-likeF: Glyco_hydro_2_NECOD (1.6)
EGlyco_hydro_2e1yq2E3 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: Glyco_hydro_2ECOD (1.6)
EDUF4981e1yq2E2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF4981ECOD (1.6)
EBgal_small_Ne1yq2E4 A: beta sandwichesX: Glycosyl hydrolase domain-likeH: supersandwich (From Topology)T: supersandwichF: Bgal_small_NECOD (1.6)
EGlyco_hydro_2_Ce1yq2E5 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Glyco_hydro_2_CECOD (1.6)
FGlyco_hydro_2_Ne1yq2F1 A: beta sandwichesX: jelly-rollH: Concanavalin A-likeT: Galactose-binding domain-likeF: Glyco_hydro_2_NECOD (1.6)
FGlyco_hydro_2e1yq2F3 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: Glyco_hydro_2ECOD (1.6)
FDUF4981e1yq2F2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF4981ECOD (1.6)
FBgal_small_Ne1yq2F4 A: beta sandwichesX: Glycosyl hydrolase domain-likeH: supersandwich (From Topology)T: supersandwichF: Bgal_small_NECOD (1.6)
FGlyco_hydro_2_Ce1yq2F5 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Glyco_hydro_2_CECOD (1.6)
DGlyco_hydro_2_Ne1yq2D1 A: beta sandwichesX: jelly-rollH: Concanavalin A-likeT: Galactose-binding domain-likeF: Glyco_hydro_2_NECOD (1.6)
DGlyco_hydro_2e1yq2D3 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: Glyco_hydro_2ECOD (1.6)
DDUF4981e1yq2D2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF4981ECOD (1.6)
DBgal_small_Ne1yq2D4 A: beta sandwichesX: Glycosyl hydrolase domain-likeH: supersandwich (From Topology)T: supersandwichF: Bgal_small_NECOD (1.6)
DGlyco_hydro_2_Ce1yq2D5 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Glyco_hydro_2_CECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A2.60.120.260 Mainly Beta Sandwich Jelly Rolls Galactose-binding domain-likeCATH (4.3.0)
A2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
A3.20.20.80 Alpha Beta Alpha-Beta Barrel TIM Barrel GlycosidasesCATH (4.3.0)
A2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase Chain A, domain 5CATH (4.3.0)
B2.60.120.260 Mainly Beta Sandwich Jelly Rolls Galactose-binding domain-likeCATH (4.3.0)
B2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
B3.20.20.80 Alpha Beta Alpha-Beta Barrel TIM Barrel GlycosidasesCATH (4.3.0)
B2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase Chain A, domain 5CATH (4.3.0)
C2.60.120.260 Mainly Beta Sandwich Jelly Rolls Galactose-binding domain-likeCATH (4.3.0)
C2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
C3.20.20.80 Alpha Beta Alpha-Beta Barrel TIM Barrel GlycosidasesCATH (4.3.0)
C2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase Chain A, domain 5CATH (4.3.0)
E2.60.120.260 Mainly Beta Sandwich Jelly Rolls Galactose-binding domain-likeCATH (4.3.0)
E2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
E3.20.20.80 Alpha Beta Alpha-Beta Barrel TIM Barrel GlycosidasesCATH (4.3.0)
E2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase Chain A, domain 5CATH (4.3.0)
F2.60.120.260 Mainly Beta Sandwich Jelly Rolls Galactose-binding domain-likeCATH (4.3.0)
F2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
F3.20.20.80 Alpha Beta Alpha-Beta Barrel TIM Barrel GlycosidasesCATH (4.3.0)
F2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase Chain A, domain 5CATH (4.3.0)
D2.60.120.260 Mainly Beta Sandwich Jelly Rolls Galactose-binding domain-likeCATH (4.3.0)
D2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
D3.20.20.80 Alpha Beta Alpha-Beta Barrel TIM Barrel GlycosidasesCATH (4.3.0)
D2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase Chain A, domain 5CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF02836Glycosyl hydrolases family 2, TIM barrel domain (Glyco_hydro_2_C)Glycosyl hydrolases family 2, TIM barrel domainThis family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.Domain
A, B, C, D, E
PF02837Glycosyl hydrolases family 2, sugar binding domain (Glyco_hydro_2_N)Glycosyl hydrolases family 2, sugar binding domainThis family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.Domain
A, B, C, D, E
PF16353Beta-galactosidase, domain 4 (LacZ_4)Beta-galactosidase, domain 4This entry represents domain 4 found in beta-galactosidase [1] and it is organised in a jelly-roll type barrel (Rutkiewicz-Krotewicz M. et al. Crystals 2018, 8(1), 13, https://doi.org/10.3390/cryst8010013).Domain
A, B, C, D, E
PF02929Beta galactosidase small chain (Bgal_small_N)Beta galactosidase small chainThis domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.Domain

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D, E
IPR032312Beta-galactosidase, domain 4Domain
A, B, C, D, E
IPR017853Glycoside hydrolase superfamilyHomologous Superfamily
A, B, C, D, E
IPR006101Glycoside hydrolase, family 2Family
A, B, C, D, E
IPR004199Beta galactosidase small chain/ domain 5Domain
A, B, C, D, E
IPR008979Galactose-binding-like domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR036156Beta-Galactosidase/glucuronidase domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR006104Glycosyl hydrolases family 2, sugar binding domainDomain
A, B, C, D, E
IPR013783Immunoglobulin-like foldHomologous Superfamily
A, B, C, D, E
IPR006103Glycoside hydrolase family 2, catalytic domainDomain
A, B, C, D, E
IPR023232Glycoside hydrolase, family 2, active siteActive Site
A, B, C, D, E
IPR023230Glycoside hydrolase, family 2, conserved siteConserved Site
A, B, C, D, E
IPR014718Glycoside hydrolase-type carbohydrate-bindingHomologous Superfamily
A, B, C, D, E
IPR050347Bacterial Beta-galactosidaseFamily
A, B, C, D, E
IPR011013Galactose mutarotase-like domain superfamilyHomologous Superfamily