Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with 15cis- retinal
Ehyaei, N., Geiger, J.H., Borhan, B.To be published.
Experimental Data Snapshot
Starting Model: experimental
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Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Retinol-binding protein 2 | 133 | Homo sapiens | Mutation(s): 8  Gene Names: RBP2, CRBP2 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P50120 (Homo sapiens) Explore P50120  Go to UniProtKB:  P50120 | |||||
PHAROS:  P50120 GTEx:  ENSG00000114113  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P50120 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 3 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
RET (Subject of Investigation/LOI) Query on RET | E [auth A], G [auth B] | RETINAL C20 H28 O NCYCYZXNIZJOKI-OVSJKPMPSA-N | |||
GOL Query on GOL | C [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N | |||
ACT Query on ACT | D [auth A], F [auth B] | ACETATE ION C2 H3 O2 QTBSBXVTEAMEQO-UHFFFAOYSA-M |
Length ( Å ) | Angle ( ˚ ) |
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a = 30.923 | α = 86.203 |
b = 36.038 | β = 86.555 |
c = 64.026 | γ = 65.059 |
Software Name | Purpose |
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PHENIX | refinement |
PHENIX | refinement |
HKL-2000 | data scaling |
PHENIX | phasing |
PDB_EXTRACT | data extraction |
Coot | model building |
HKL-2000 | data processing |
HKL-2000 | data reduction |
Funding Organization | Location | Grant Number |
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National Institutes of Health/National Center for Research Resources (NIH/NCRR) | United States | -- |