THR
THREONINE
Find entries where: THR
is present as a standalone ligand in 33 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 17 entries
is present in a polymer sequence 220,622 entries
Chemical Component Summary | |
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Name | THREONINE |
Identifiers | (2S,3R)-2-amino-3-hydroxy-butanoic acid |
Formula | C4 H9 N O3 |
Molecular Weight | 119.119 |
Type | L-PEPTIDE LINKING |
Isomeric SMILES | C[C@H]([C@@H](C(=O)O)N)O |
InChI | InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1 |
InChIKey | AYFVYJQAPQTCCC-GBXIJSLDSA-N |
Chemical Details | |
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Formal Charge | 0 |
Atom Count | 17 |
Chiral Atom Count | 2 |
Bond Count | 16 |
Aromatic Bond Count | 0 |
Drug Info: DrugBank
DrugBank ID | DB00156 |
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Name | Threonine |
Groups |
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Description | An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins. |
Synonyms |
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Brand Names |
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Indication | L-Threonine makes up collagen, elastin, and enamel protein. It aids proper fat metabolism in the liver, helps the digestive and intestinal tracts function more smoothly, and assists in metabolism and assimilation. |
Categories |
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CAS number | 72-19-5 |
Drug Targets
Name | Target Sequence | Pharmacological Action | Actions |
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Threonine--tRNA ligase, cytoplasmic | MFEEKASSPSGKMGGEEKPIGAGEEKQKEGGKKKNKEGSGDGGRAELNPW... | unknown | |
Threonine--tRNA ligase, mitochondrial | MALYQRWRCLRLQGLQACRLHTAVVSTPPRWLAERLGLFEELWAAQVKRL... | unknown | |
Beta-lactamase Toho-1 | MMTQSIRRSMLTVMATLPLLFSSATLHAQANSVQQQLEALEKSSGGRLGV... | unknown | unknown |
Monocarboxylate transporter 10 | MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVEL... | unknown | inhibitor |
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
Resource Name | Reference |
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PubChem | 6288, 6971019 |
ChEMBL | CHEMBL291747 |
ChEBI | CHEBI:16857, CHEBI:57926 |
CCDC/CSD | MOVLOZ, MOVLOZ01, ATONAZ, YEJTIQ, IYEBIX, ETEYOR, HULGAW, MESTEM, GUQKAG |