Chemical Component Summary

Name2-HYDROXYBENZOIC ACID
SynonymsSALICYLIC ACID
Identifiers2-hydroxybenzoic acid
FormulaC7 H6 O3
Molecular Weight138.121
TypeNON-POLYMER
Isomeric SMILESc1ccc(c(c1)C(=O)O)O
InChIInChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChIKeyYGSDEFSMJLZEOE-UHFFFAOYSA-N

Chemical Details

Formal Charge0
Atom Count16
Chiral Atom Count0
Bond Count16
Aromatic Bond Count6

Drug Info: DrugBank

DrugBank IDDB00936 
NameSalicylic acid
Groups
  • approved
  • investigational
  • vet_approved
DescriptionA compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Synonyms
  • Salicylic acid
  • Sodium salicylate
  • Diethylamine salicylate
  • 2-Carboxyphenol
  • ácido salicílico
Brand Names
  • Clearskin Blemish Clearing Overnight Treatment
  • Nas Max Strength Spot Treatment
  • Black Bean Anti Hair Loss Root Tonic
  • OXY Hydrating Body Wash
  • Defense Acne Care 2% Salicylic Acid
IndicationKey additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts.
Categories
  • Acids, Carbocyclic
  • Agents causing hyperkalemia
  • Agents that produce hypertension
  • Analgesics
  • Analgesics, Non-Narcotic
ATC-Code
  • D01AE12
  • N02BA04
  • N02BA12
  • S01BC08
CAS number69-72-7

Drug Targets

NameTarget SequencePharmacological ActionActions
Prostaglandin G/H synthase 1MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFG...unknowninhibitor
Prostaglandin G/H synthase 2MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFY...unknowninhibitor
Aldo-keto reductase family 1 member C1MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHID...unknowninhibitor
Cytochrome P450 2C9MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDI...unknownsubstrate
Serum albuminMKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...unknownother/unknown
View More
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
Pharos CHEMBL424
PubChem 118212070, 338
ChEMBL CHEMBL424
ChEBI CHEBI:16914
CCDC/CSD HAGTOY, BUVBIG, BUVBIG02, HUWHAK, KUJDIE, GEYSAE02, EJIFIO, IFEFUX, GOKQUV01, BUVBIG01, DKPSAL10, DOGCAG, LATLAV, CIXMED, GOKQUV, ENICEK, BULKOK, EZEGIA, KOPKEH, LATKUO, HOYXIE, IFEFOR, CEKNEN, KIGLES, GEYSAE, DUPXEU, HOGFEQ, ACETAF, GIHCAD, CARTEW, HUNJIL, KIGLES01, BULJID, DUPXIY, KIJKUL, APYSAL, IZAHEZ, KOPKEH01, CUWFIM, AVEHER, GAHZOI, KOPKEH02, AQEJEO
COD 2100548, 2022076, 4504244, 1519837, 4503560, 7214357, 7208274, 4500305