PAL

N-(PHOSPHONACETYL)-L-ASPARTIC ACID

Find entries where: PAL

is present as a standalone ligand in 24 entries

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Chemical Component Summary
Name	N-(PHOSPHONACETYL)-L-ASPARTIC ACID
Identifiers	(2S)-2-(2-phosphonoethanoylamino)butanedioic acid
Formula	C₆ H₁₀ N O₈ P
Molecular Weight	255.119
Type	NON-POLYMER
Isomeric SMILES	C([C@@H](C(=O)O)NC(=O)CP(=O)(O)O)C(=O)O
InChI	InChI=1S/C6H10NO8P/c8-4(2-16(13,14)15)7-3(6(11)12)1-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)(H2,13,14,15)/t3-/m0/s1
InChIKey	ZZKNRXZVGOYGJT-VKHMYHEASA-N

Chemical Details
Formal Charge	0
Atom Count	26
Chiral Atom Count	1
Bond Count	25
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB03459
Name	Sparfosic acid
Groups	experimental
Description	Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen atom. This substance is known to target aspartate carbamoyltransferase catalytic chain and CAD protein.
Synonyms	PALA Acidum sparfosicum N-(phosphonacetyl)-L-aspartic acid phosphonoacetyl-L-aspartic acid N-(phosphonoacetyl)-L-aspartic acid ácido esparfósico Sparfosic acid N-phosphonacetyl-L-aspartic acid
Categories	Acetates Acids, Acyclic Amino Acids Amino Acids, Acidic Amino Acids, Dicarboxylic Amino Acids, Peptides, and Proteins Anti-Infective Agents Antimetabolites Antineoplastic Agents Enzyme Inhibitors Excitatory Amino Acids Noxae Organophosphonates Organophosphorus Compounds Toxic Actions
CAS number	51321-79-0

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Aspartate carbamoyltransferase catalytic chain	MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKVIASCFF...	unknown
CAD protein	MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQIL...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682