G

GUANOSINE-5'-MONOPHOSPHATE

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is present as a standalone ligand in 6 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 1 entries

is present in a polymer sequence 7,727 entries

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Chemical Component Summary
Name	GUANOSINE-5'-MONOPHOSPHATE
Identifiers	[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate
Formula	C₁₀ H₁₄ N₅ O₈ P
Molecular Weight	363.221
Type	RNA LINKING
Isomeric SMILES	c1nc2c(n1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)N=C(NC2=O)N
InChI	InChI=1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
InChIKey	RQFCJASXJCIDSX-UUOKFMHZSA-N

Chemical Details
Formal Charge	0
Atom Count	38
Chiral Atom Count	4
Bond Count	40
Aromatic Bond Count	5

Drug Info: DrugBank

DrugBank ID	DB01972
Name	Guanosine-5'-Monophosphate
Groups	experimental
Description	Guanosine 5'-monophosphate. A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. [PubChem]
Synonyms	Guanosine-5'-Monophosphate
CAS number	85-32-5

Drug Targets

Name	Target Sequence	Pharmacological Action
Guanylate kinase	MSGPRPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENG...	unknown
Response regulator PleD	MSARILVVDDIEANVRLLEAKLTAEYYEVSTAMDGPTALAMAARDLPDII...	unknown
DNA polymerase	MKEFYLTVEQIGDSIFERYIDSNGRERTREVEYKPSLFAHCPESQATKYF...	unknown
Disks large homolog 4	MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGY...	unknown
GMP reductase 1	MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPI...	unknown
cGMP-specific 3',5'-cyclic phosphodiesterase	MERAGPSFGQQRQQQQPQQQKQQQRDQDSVEAWLDDHWDFTFSYFVRKAT...	unknown
Histidine triad nucleotide-binding protein 1	MADEIAKAQVARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPT...	unknown
Bifunctional purine biosynthesis protein PURH	MAPGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRD...	unknown
Amidophosphoribosyltransferase	MLAEIKGLNEECGVFGIWGHEEAPQITYYGLHSLQHRGQEGAGIVATDGE...	unknown
Protein-glutamine gamma-glutamyltransferase E	MAALGVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKGLGS...	unknown
Bifunctional protein PyrR	MQKAVVMDEQAIRRALTRIAHEIIERNKGIDGCVLVGIKTRGIYLARRLA...	unknown
Xanthine phosphoribosyltransferase	MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLAREL...	unknown
Amidophosphoribosyltransferase	MCGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFRLRKANG...	unknown
Bifunctional adenosylcobalamin biosynthesis protein CobU	MMILVTGGARSGKSRHAEALIGDAPQVLYIATSQILDDEMAARIQHHKDG...	unknown
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682