D11

D-PHOSPHOTHREONINE

Created:	2006-11-15
Last modified:	2024-09-27

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1 entries where D11 is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	22
Chiral Atom Count	2
Bond Count	21
Aromatic Bond Count	0

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Chemical Component Summary
Name	D-PHOSPHOTHREONINE
Synonyms	O-PHOSPHONO-D-THREONINE
Systematic Name (OpenEye OEToolkits)	(2R,3S)-2-amino-3-phosphonooxy-butanoic acid
Formula	C₄ H₁₀ N O₆ P
Molecular Weight	199.099
Type	D-PEPTIDE LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=P(O)(O)OC(C(N)C(=O)O)C
SMILES	CACTVS	3.341	C[CH](O[P](O)(O)=O)[CH](N)C(O)=O
SMILES	OpenEye OEToolkits	1.5.0	CC(C(C(=O)O)N)OP(=O)(O)O
Canonical SMILES	CACTVS	3.341	C[C@H](O[P](O)(O)=O)[C@@H](N)C(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C[C@@H]([C@H](C(=O)O)N)OP(=O)(O)O
InChI	InChI	1.03	InChI=1S/C4H10NO6P/c1-2(3(5)4(6)7)11-12(8,9)10/h2-3H,5H2,1H3,(H,6,7)(H2,8,9,10)/t2-,3+/m0/s1
InChIKey	InChI	1.03	USRGIUJOYOXOQJ-STHAYSLISA-N

Drug Info: DrugBank

DrugBank ID	DB02482
Name	Phosphonothreonine
Groups	experimental
Description	The phosphoric acid ester of threonine. Used as an identifier in the analysis of peptides, proteins, and enzymes. [PubChem]
Synonyms	Phosphonothreonine

Drug Targets

Name	Target Sequence	Pharmacological Action
Protein kinase C theta type	MSPFLRIGLSNFDCGSCQSCQGEAVNPYCAVLVKEYVESENGQMYIQKKP...	unknown
Aurora kinase A	MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCP...	unknown
Mitogen-activated protein kinase 1	MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVR...	unknown
cAMP-dependent protein kinase catalytic subunit alpha	MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTL...	unknown
cAMP-dependent protein kinase catalytic subunit beta	MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTL...	unknown
Cyclin-dependent kinase 7	MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSE...	unknown
Threonine-phosphate decarboxylase	MALFNSAHGGNIREAATVLGISPDQLLDFSANINPLGMPVSVKRALIDNL...	unknown
Rhodopsin	MNGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVL...	unknown
Protein S100-A11	MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAF...	unknown
Mitogen-activated protein kinase 12	MSSPPPARSGFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDGRTG...	unknown
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682