ARG

ARGININE

Find entries where: ARG

is present as a standalone ligand in 260 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 14 entries

is present in a polymer sequence 220,306 entries

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Chemical Component Summary
Name	ARGININE
Identifiers	[amino-[[(4S)-4-amino-5-hydroxy-5-oxo-pentyl]amino]methylidene]azanium
Formula	C₆ H₁₅ N₄ O₂
Molecular Weight	175.209
Type	L-PEPTIDE LINKING
Isomeric SMILES	C(C[C@@H](C(=O)O)N)CNC(=[NH2+])N
InChI	InChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/p+1/t4-/m0/s1
InChIKey	ODKSFYDXXFIFQN-BYPYZUCNSA-O

Chemical Details
Formal Charge	1
Atom Count	27
Chiral Atom Count	1
Bond Count	26
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB00125
Name	Arginine
Groups	investigational nutraceutical
Description	An essential amino acid that is physiologically active in the L-form.
Synonyms	(2S)-2-amino-5-(carbamimidamido)pentanoic acid L-Arginin L-(+)-Arginine Arginina Arginine butyrate R L-Arg (S)-2-Amino-5-guanidinovaleric acid L-arginine Arginine hydrochloride (2S)-2-amino-5-guanidinopentanoic acid Arg Arginine (S)-2-amino-5-guanidinopentanoic acid
Brand Names	4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Premasol - sulfite-free (Amino Acid) Aminosyn-PF 10% Hypertenevide-12.5 FreAmine III Travasol E Renamin (amino Acids) Injection 5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose ProcalAmine 2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix Aminosyn Sulfite Free Travasol L-arginine Hydrochloride Injection 2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Olimel 3.3% E Aminosyn RF Injection Clinisol Lytensopril-90 Primene 10%-liq IV 4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix Aminosyn II with Electrolytes Smofkabiven Vamin N Smofkabiven Extra Nitrogen Electrolyte Free 4.25%trav. Amino Acid InJ.W.O.elect.5%dext. Periolimel 2.5% E 2.5%travasol Amino Acid InJ.W.eleC.W.25%dex Plenamine Aminosyn 5% Lytensopril RenAmin 2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix 2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix Primene 10% Novamine Aminosyn II 7% M In 10% Dextrose(dual Chamber) Perikabiven Olimel 5.7% E 2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix 2.75%travasol Amino Acid InJ.W.eleC.W.5%dex. tensioSAN Aminosyn RF Essepna 4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose 5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose 4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Aminosyn 10% W Electrolytes Aminosyn Aminosyn II 5% Inj Olimel 4.4% Aminosyn II Aminosyn II in Dextrose HepatAmine Aminosyn II 7% With 10% Dextrose 4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec Travasol Amino Acid Inj 8.5% 8.5% Freamine III 4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix Smofkabiven Peripheral Aminosyn 7% Travasol Amino Acid Inj 5.5% 4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Aminosyn II 8.5% Injection Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec Olimel 4.4% E Olimel 5.7% 2.75% Travas. Amino Acid InJ.W.elecw.25%dex Synthamin Aminosyn 8.5% Vamin 18 Electrolyte-free Lysakare Smofkabiven Extra Nitrogen 4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix Aminosyn II 8.5% With 50% Dextrose Nutrineal Pd4 Aminosyn II with Electrolytes in Dextrose with Calcium Aminosyn II In Dextrose Injection Aminosyn II 8.5% M In 20% Dextrose (dual Chamber) R-Gene Primene Smofkabiven Electrolyte Free Hypertensolol Aminosyn HF 4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix Travasol Inj Without Electrolytes 8.5% Kabiven Arginine 20% Prosol Hepatasol Travasol Inj Without Electrolytes 5.5% Repair Vaginal Aminosyn-PF Aminosyn II and Dextrose Rimantalist Aminosyn 3.5% M ProSol Aminosyn II 7% Injection Clinimix FreAmine HBC Aminosyn 8.5% Injection With Electrolytes Aminosyn II 7% With 50% Dextrose Moisture Cushion Aminosyn II 10% With Electrolytes Hypertenipine 5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Aminosyn-PF 7% Cream Clinimix E TrophAmine Cardiotek-RX Olimel 7.6% Olimel 7.6% E 4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose 4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Indication	Used for nutritional supplementation, also for treating dietary shortage or imbalance.
Categories	Acids, Acyclic Amino Acids Amino Acids, Basic Amino Acids, Diamino Amino Acids, Peptides, and Proteins Arginine Blood and Blood Forming Organs Blood Substitutes and Perfusion Solutions Detoxifying Agents for Antineoplastic Treatment Dietary Supplements Fatty Acids Fatty Acids, Volatile I.V. Solution Additives Lipids Pituitary Function Proteinogenic Amino Acids Supplements
ATC-Code	V03AF11 B05XB01
CAS number	74-79-3

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Cationic amino acid transporter 3	MPWQAFRRFGQKLVRRRTLESGMAETRLARCLSTLDLVALGVGSTLGAGV...	unknown
Arginine decarboxylase	MAGYLSESDFVMVEEGFSTRDLLKELTLGASQATTDEVAAFFVADLGAIV...	unknown
Argininosuccinate lyase	MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLE...	unknown
Nitric oxide synthase, inducible	MACPWKFLFKTKFHQYAMNGEKDINNNVEKAPCATSSPVTQDDLQYHNLS...	unknown
High affinity cationic amino acid transporter 1	MGCKVLLNIGQQMLRRKVVDCSREETRLSRCLNTFDLVALGVGSTLGAGV...	unknown
Arginase-2, mitochondrial	MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIR...	unknown
Cationic amino acid transporter 4	MARGLPTIASLARLCQKLNRLKPLEDSTMETSLRRCLSTLDLTLLGVGGM...	unknown
Argininosuccinate synthase	MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKK...	unknown
Nitric oxide synthase, endothelial	MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAP...	unknown
Solute carrier family 22 member 5	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Monocarboxylate transporter 10	MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVEL...	unknown	inhibitor
Solute carrier family 22 member 4	MRDYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRC...	unknown	inhibitor
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
PubChem	52941769, 1549073, 5287702, 59294017, 88031296, 59904234
ChEBI	CHEBI:32682
CCDC/CSD	GELHIO10, NABSIT, INEFIQ01, HAHBIC01, REHTII, BOQVIM01, PEVCUR, ORUXEF, NABQAJ, EGIVOH, ARGBRH02, MOSRAQ, HAHBIC, NABSOZ, EGIVUN, EGIVIB, ADIHOL, BOQVIM, QIJZEQ, MACMUC
COD	2209573

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

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ARG

ARGININE

Chemical Component Summary

Chemical Details

Drug Info: DrugBank

Drug Targets

Related Resource References