AMP

ADENOSINE MONOPHOSPHATE

Find entries where: AMP

is present as a standalone ligand in 837 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 125 entries

is present in a polymer sequence 1 entries

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Chemical Component Summary
Name	ADENOSINE MONOPHOSPHATE
Identifiers	[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate
Formula	C₁₀ H₁₄ N₅ O₇ P
Molecular Weight	347.221
Type	NON-POLYMER
Isomeric SMILES	c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)N
InChI	InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChIKey	UDMBCSSLTHHNCD-KQYNXXCUSA-N

Chemical Details
Formal Charge	0
Atom Count	37
Chiral Atom Count	4
Bond Count	39
Aromatic Bond Count	10

Drug Info: DrugBank

DrugBank ID	DB00131
Name	Adenosine phosphate
Groups	approved investigational withdrawn nutraceutical
Description	Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.[L43937]
Synonyms	5'-Adenosine monophosphate Adenylate Adenosine-5'-Monophosphate Adenosini phosphas 5'-AMP Adenosine monophosphate Adenosine 5'-phosphate Adenosine-5'P Phosphate d'adénosine 5'-Adenylic acid Adenosine-5'-monophosphoric acid Fosfato de adenosina Ado5'P Adenosine 5'-(dihydrogen phosphate) Adenosine phosphate AMP 5'-O-Phosphonoadenosine PAdo Adenylic acid Adenosine 5'-monophosphate
Indication	For nutritional supplementation, also for treating dietary shortage or imbalance
Categories	Adenine Nucleotides Dietary Supplements Heterocyclic Compounds, Fused-Ring Nucleic Acids, Nucleotides, and Nucleosides Nucleotides Purine Nucleotides Purines Ribonucleotides Supplements
CAS number	61-19-8

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
5'-AMP-activated protein kinase	MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTG...	unknown	activator
Adenosine kinase	MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSL...	unknown	product of
5'-AMP-activated protein kinase subunit beta-1	MGNTSSERAALERHGGHKTPRRDSSGGTKDGDRPKILMDSPEDADLFHSE...	unknown	activator
Acetyl-coenzyme A synthetase, cytoplasmic	MGLPEERVRSGSGSRGQEEAGAGGRARSWSPPPEVSRSAHVPSLQRYREL...	unknown	product of
5'-AMP-activated protein kinase catalytic subunit alpha-1	MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTG...	unknown	activator
Adenylate cyclase type 1	MAGAPRGGGGGGGGAGEPGGAERAAGTSRRRGLRACDEEFACPELEALFR...	unknown	product of
Long-chain-fatty-acid--CoA ligase 1	MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKP...	unknown	product of
Cyclic AMP-responsive element-binding protein 1	MTMESGAENQQSGDAAVTEAENQQMTVQAQPQIATLAQVSMPAAHATSSA...	unknown	activator
DNA	-	unknown	component of
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	MKKSRSVMTVMADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNL...	unknown	product of
Glycogen phosphorylase, liver form	-	unknown	activator
Histidine triad nucleotide-binding protein 1	MADEIAKAQVARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPT...	unknown	product of
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	MEAEGSSAPARAGSGEGSDSAGGATLKAPKHLWRHEQHHQYPLRQPQFRL...	unknown	product of
Fructose-1,6-bisphosphatase 1	MADQAPFDTDVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVR...	unknown	antagonist
AMP deaminase 1	MNVRIFYSVSQSPHSLLSLLFYCAILESRISATMPLFKLPAEEKQIDDAM...	unknown	substrate
Adenine phosphoribosyltransferase	MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHL...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682