ADE

ADENINE

Find entries where: ADE

is present as a standalone ligand in 191 entries

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Chemical Component Summary
Name	ADENINE
Identifiers	9H-purin-6-amine
Formula	C₅ H₅ N₅
Molecular Weight	135.127
Type	NON-POLYMER
Isomeric SMILES	c1[nH]c2c(n1)c(ncn2)N
InChI	InChI=1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)
InChIKey	GFFGJBXGBJISGV-UHFFFAOYSA-N

Chemical Details
Formal Charge	0
Atom Count	15
Chiral Atom Count	0
Bond Count	16
Aromatic Bond Count	10

Drug Info: DrugBank

DrugBank ID	DB00173
Name	Adenine
Groups	approved nutraceutical
Description	A purine base and a fundamental unit of adenine nucleotides.
Synonyms	Adenin Adenine Vitamin B4 Adenine hydrochloride Adenine sulfate 6-Aminopurine
Brand Names	Haemonetics Additive Solution Formula 3 (AS-3) Cpda-1 Leucoflex CGP As 3 Additive Solution Formula 3 As-3 Leukotrap - AS-3 Solution TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose Adenine (CPDA-1) TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL Red Cell Preservative Cpd Adenine Cpda 1 Additive Formula 3 As-3 IMUFLEX WB-RP Blood Bag System with Integral Whole Blood Leukocyte Reduction Filter (Removing Platelets) with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL (AS-5) Red Cell Preservative CPDA-1 Blood Collection System IMUFLEX WB-SP Blood Bag System with Integral Whole Blood Leukocyte Reduction Filter (Saving Platelets) with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) and OPTISOL (AS-5) Red Cell Preservative Additive Solution Sodium Adenine Glucose Mannitol (sagm) Sag-M Leukotrap WB System - AS3 Leukotrap - AS-3 Rejuvesol Leukotrap TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL (AS-5) Red Cell Preservative TERUFLEX Blood Bag System with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL (AS-5) Red Cell Preservative Anticoagulant Cit Phos Dex Adenine Sol USP CPD/ADSOL Red Cell Preservation Solution System (PL 2209) Adsol Red Cell Preservation MTL1 Leucoflex ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) Leukotrap WB System Cpd/adsol Nutricel Additive Solution - AS-3 Sag-mannitol Solution
Indication	For nutritional supplementation, also for treating dietary shortage or imbalance
Categories	Dietary Supplements Heterocyclic Compounds, Fused-Ring Purines Supplements UGT1A1 Inhibitors
CAS number	73-24-5

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Adenine phosphoribosyltransferase	MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHL...	unknown
DNA	-	unknown
S-methyl-5'-thioadenosine phosphorylase	MASGTTTTAVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKI...	unknown
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	MQTLHALLRDIPAPDAEAMARAQQHIDGLLKPPGSLGRLETLAVQLAGMP...	unknown
Acetyl-CoA carboxylase 2	MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPSQEPFPA...	unknown
Low molecular weight phosphotyrosine protein phosphatase	MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGY...	unknown
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVALLKSGI...	unknown
Peroxisomal trans-2-enoyl-CoA reductase	MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASR...	unknown
A/G-specific adenine glycosylase	MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIP...	unknown
Nucleoside deoxyribosyltransferase-I	MKAVVPTGKIYLGSPFYSDAQRERAAKAKELLAKNPSIAHVFFPFDDGFT...	unknown
SRSF protein kinase 2	MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEIL...	unknown
Holliday junction ATP-dependent DNA helicase RuvB	MEDLALRPKTLDEYIGQERLKQKLRVYLEAAKARKEPLEHLLLFGPPGLG...	unknown
UDP-glucuronosyltransferase 1-1	MAVESQGGRPLVLGLLLCVLGPVVSHAGKILLIPVDGSHWLSMLGAIQQL...	unknown	inhibitor
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682