SAbDab Antibody Annotation SAbDab Database Homepage

ChainChain ClassChain SubclassChain TypeAntigen Name(s) Provenance Source
D [auth H],
F [auth D],
H [auth F]
Heavy ChainIGHV3 -factor h-binding proteinSAbDab (2024-11-29)
E [auth L],
G [auth E],
I [auth G]
Light ChainIGKV3 Kappafactor h-binding proteinSAbDab (2024-11-29)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C
PF08794Factor H binding protein, C-terminal (FHBP_C)Factor H binding protein, C-terminalFactor H binding protein (also known as GNA1870) is a surface exposed lipoprotein in Neisseria meningitidis that is a potent antigen and a potential candidate for a vaccine against meningococcal disease [1-4]. The structure of the C-terminal domain c ...Factor H binding protein (also known as GNA1870) is a surface exposed lipoprotein in Neisseria meningitidis that is a potent antigen and a potential candidate for a vaccine against meningococcal disease [1-4]. The structure of the C-terminal domain consists of an anti-parallel beta barrel overlaid by a short alpha helical region [1,5]. This domain is highly similar to Transferrin-binding protein B beta barrel (Pfam:PF01298).
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C
Factor H-binding protein- -
D [auth H],
F [auth D],
H [auth F]
Fab Heavy chain---
E [auth L],
G [auth E],
I [auth G]
Fab light Chains---