6JB8
Crystal structure of nanobody D3-L11 in complex with hen egg-white lysozyme
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d6jb8a_ | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | V set domains (antibody variable domain-like) | automated matches | (Camelus dromedarius ) [TaxId: 9838 ], | SCOPe (2.08) |
B | d6jb8b_ | Alpha and beta proteins (a+b) | Lysozyme-like | Lysozyme-like | C-type lysozyme | Lysozyme | (Gallus gallus ) [TaxId: 9031 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | V-set_12 | e6jb8A1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_12 | ECOD (1.6) |
B | Lys | e6jb8B1 | A: a+b complex topology | X: Lysozyme-like (From Homology) | H: Lysozyme-like | T: Lysozyme-like | F: Lys | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 1.10.530.10 | Mainly Alpha | Orthogonal Bundle | Lysozyme | CATH (utative) |
IMGT Antibody Annotation IMGT Database Homepage
Chain | Protein Name | Description | Organism Name | Gene Allele Name(s) | Domain Name(s) | Receptor Type | Receptor Description | Provenance Source |
---|---|---|---|---|---|---|---|---|
nAb D3-L11, anti-lysozyme C [hen egg white] | VH | Camelus dromedarius (Arabian camel) | IGHV3S45*01, IGHJ4*01 | V-DOMAIN VH | IG | VH | IMGT (202448-0) |
SAbDab Antibody Annotation SAbDab Database Homepage
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
---|---|---|---|---|---|
Heavy Chain | IGHV1 | - | lysozyme c | SAbDab (2024-12-06) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00062 | C-type lysozyme/alpha-lactalbumin family (Lys) | C-type lysozyme/alpha-lactalbumin family | Alpha-lactalbumin is the regulatory subunit of lactose synthase, changing the substrate specificity of galactosyltransferase from N-acetylglucosamine to glucose. C-type lysozymes are secreted bacteriolytic enzymes that cleave the peptidoglycan of bac ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR001916 | Glycoside hydrolase, family 22 | Family | |
IPR023346 | Lysozyme-like domain superfamily | Homologous Superfamily | |
IPR019799 | Glycoside hydrolase family 22 domain | Domain | |
IPR000974 | Glycoside hydrolase, family 22, lysozyme | Family |