6G95
Crystal structure of Ebolavirus glycoprotein in complex with thioridazine
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d6g95a1 | Membrane and cell surface proteins and peptides | Filovirus surface glycoprotein-like | Filovirus surface glycoprotein-like | Filovirus surface glycoproteins | Ebolavirus surface glycoprotein | ZEBOV (Ebola virus - Mayinga, Zaire, 1976 ) [TaxId: 128952 ], | SCOPe (2.08) |
A | d6g95a2 | Artifacts | Tags | Tags | Tags | C-terminal Tags | ZEBOV (Ebola virus - Mayinga, Zaire, 1976 ) [TaxId: 128952 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Filo_glycop | e6g95A1 | A: a+b complex topology | X: Envelope glycoprotein GP1 (From Topology) | H: Envelope glycoprotein GP1 (From Topology) | T: Envelope glycoprotein GP1 | F: Filo_glycop | ECOD (1.6) |
B | Ebola-like_HR1-HR2 | e6g95B1 | A: a+b duplicates or obligate multimers | X: Envelope glycoprotein GP2-related (From Topology) | H: Envelope glycoprotein GP2-related (From Topology) | T: Envelope glycoprotein GP2-related | F: Ebola-like_HR1-HR2 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF01611 | Filovirus glycoprotein (Filo_glycop) | Filovirus glycoprotein | - | Family | |
PF22307 | Envelope glycoprotein GP2-like, HR1-HR2 (Ebola-like_HR1-HR2) | Envelope glycoprotein GP2-like, HR1-HR2 | This entry spans heptad repeats 1 and 2 of the glycoprotein (GP) from Ebola and Marburg viruses [1-5]. Viral infection involves the formation of a trimer-of-hairpins structure (three HR1s helices, buttressed by three HR2 helices lying in antiparallel ... | Domain |