Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ASNFe6awoA1 A: alpha complex topologyX: Sodium:neurotransmitter symporter family (SNF)-like (From Topology)H: Sodium:neurotransmitter symporter family (SNF)-like (From Topology)T: Sodium:neurotransmitter symporter family (SNF)-likeF: SNFECOD (1.6)
BV-set_8e6awoB2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_8ECOD (1.6)
BC1-set_1e6awoB1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
CC1-set_4e6awoC2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
CV-sete6awoC1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
B2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
C2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)

IMGT Antibody Annotation IMGT Database Homepage

ChainProtein NameDescriptionOrganism NameGene Allele Name(s)Domain Name(s)Receptor TypeReceptor DescriptionProvenance Source
Fab 8B6 VH-CH1 Mus musculus (house mouse) IGHV1-26*01, IGHJ2*01, IGHG2B*02 V-DOMAIN VH, C-DOMAIN CH1 IG FAB-GAMMA-2B_KAPPA IMGT (202448-0)
Fab 8B6 L-KAPPA Mus musculus (house mouse) IGKV6-17*01, IGKJ1*01, IGKJ2*01, IGKC*01, IGKC*02 V-DOMAIN V-KAPPA, C-DOMAIN C-KAPPA IG FAB-GAMMA-2B_KAPPA IMGT (202448-0)

SAbDab Antibody Annotation SAbDab Database Homepage

ChainChain ClassChain SubclassChain TypeAntigen Name(s) Provenance Source
Heavy ChainIGHV1 -sodium-dependent serotonin transporterSAbDab (2024-12-06)
Light ChainIGKV6 Kappasodium-dependent serotonin transporterSAbDab (2024-12-06)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF00209Sodium:neurotransmitter symporter family (SNF)Sodium:neurotransmitter symporter family- Family
PF07686Immunoglobulin V-set domain (V-set)Immunoglobulin V-set domainThis domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.Domain
PF07654Immunoglobulin C1-set domain (C1-set)Immunoglobulin C1-set domain- Domain
PF07686Immunoglobulin V-set domain (V-set)Immunoglobulin V-set domainThis domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.Domain
PF07654Immunoglobulin C1-set domain (C1-set)Immunoglobulin C1-set domain- Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Sodium-dependent serotonin transporter
8B6 antibody FAB heavy chain - -
8B6 antibody FAB light chain- - -