Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
C [auth B]d5yulb_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
D [auth C]d5yulc_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
E [auth D]d5yuld_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
G [auth F]d5yulf_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
H [auth G]d5yulg_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Id5yuli_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Jd5yulj_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Ad5yula_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
B [auth H]d5yulh_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
F [auth E]d5yule_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
C [auth B]SCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
D [auth C]SCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
E [auth D]SCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
G [auth F]SCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
H [auth G]SCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
ISCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
JSCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
B [auth H]SCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
F [auth E]SCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
C [auth B]Sod_Cue5yulB1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
D [auth C]Sod_Cue5yulC1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
E [auth D]Sod_Cue5yulD1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
G [auth F]Sod_Cue5yulF1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
H [auth G]Sod_Cue5yulG1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
ISod_Cue5yulI1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
JSod_Cue5yulJ1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
ASod_Cue5yulA1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
B [auth H]Sod_Cue5yulH1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
F [auth E]Sod_Cue5yulE1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF00080Copper/zinc superoxide dismutase (SODC) (Sod_Cu)Copper/zinc superoxide dismutase (SODC)superoxide dismutases (SODs) catalyse the conversion of superoxide radicals to hydrogen peroxide and molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the human SO ...superoxide dismutases (SODs) catalyse the conversion of superoxide radicals to hydrogen peroxide and molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the human SOD1 gene cause familial amyotrophic lateral sclerosis (Lou Gehrig's disease). Structure is an eight-stranded beta sandwich, similar to the immunoglobulin fold.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Superoxide dismutase [Cu-Zn]

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
PharosP00441