Annotations: 5Y0S

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	UNK_F_TYPE	e5y0sB1	A: alpha arrays	X: HhH/H2TH	H: UPF0348 protein MJ0951 C-terminal domain (From Topology)	T: UPF0348 protein MJ0951 C-terminal domain	F: UNK_F_TYPE	ECOD (1.6)
B	HIGH_NTase1_ass_N	e5y0sB2	A: a/b three-layered sandwiches	X: HUP domain-like	H: HUP domains (From Topology)	T: HUP domains	F: HIGH_NTase1_ass_N	ECOD (1.6)
C	UNK_F_TYPE	e5y0sC2	A: alpha arrays	X: HhH/H2TH	H: UPF0348 protein MJ0951 C-terminal domain (From Topology)	T: UPF0348 protein MJ0951 C-terminal domain	F: UNK_F_TYPE	ECOD (1.6)
C	HIGH_NTase1_ass_N	e5y0sC1	A: a/b three-layered sandwiches	X: HUP domain-like	H: HUP domains (From Topology)	T: HUP domains	F: HIGH_NTase1_ass_N	ECOD (1.6)
D	UNK_F_TYPE	e5y0sD2	A: alpha arrays	X: HhH/H2TH	H: UPF0348 protein MJ0951 C-terminal domain (From Topology)	T: UPF0348 protein MJ0951 C-terminal domain	F: UNK_F_TYPE	ECOD (1.6)
D	HIGH_NTase1_ass_N	e5y0sD1	A: a/b three-layered sandwiches	X: HUP domain-like	H: HUP domains (From Topology)	T: HUP domains	F: HIGH_NTase1_ass_N	ECOD (1.6)
A	UNK_F_TYPE	e5y0sA2	A: alpha arrays	X: HhH/H2TH	H: UPF0348 protein MJ0951 C-terminal domain (From Topology)	T: UPF0348 protein MJ0951 C-terminal domain	F: UNK_F_TYPE	ECOD (1.6)
A	HIGH_NTase1_ass_N	e5y0sA1	A: a/b three-layered sandwiches	X: HUP domain-like	H: HUP domains (From Topology)	T: HUP domains	F: HIGH_NTase1_ass_N	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF05636	HIGH Nucleotidyl Transferase (HIGH_NTase1)	HIGH Nucleotidyl Transferase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Thermotoga maritima TmcAL	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding RNA binding tRNA binding nucleic acid binding catalytic activity ligase activity, forming carbon-nitrogen bonds ligase activity	tRNA modification RNA metabolic process primary metabolic process gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process RNA modification biosynthetic process tRNA processing macromolecule modification tRNA modification RNA metabolic process primary metabolic process gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process RNA modification biosynthetic process tRNA processing macromolecule modification metabolic process cellular process macromolecule metabolic process RNA processing	cellular anatomical structure intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR014729	Rossmann-like alpha/beta/alpha sandwich fold	Homologous Superfamily
A, B, C, D	IPR008513	tRNA(Met) cytidine acetate ligase	Family

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A, B, C, D	CME	Parent Component: CYS
A, B, C, D	CSD	Parent Component: CYS RESID: AA0262 PSI-MOD : L-cysteine sulfinic acid MOD:00267

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.