Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
BSCOP2B SuperfamilyToprim domain-like 8090033 3000737 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyToprim domain-like 8090033 3000737 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
BgyrB_1st_3e5btcB2 A: a+b two layersX: SSHS domainH: SSHS domain in type II DNA topoisomerase (From Topology)T: SSHS domain in type II DNA topoisomeraseF: gyrB_1st_3ECOD (1.6)
BDNA_gyraseB_Ce5btcB1 A: a/b three-layered sandwichesX: HAD domain-likeH: HAD domain-relatedT: Toprim domainF: DNA_gyraseB_CECOD (1.6)
DgyrB_1st_3e5btcD2 A: a+b two layersX: SSHS domainH: SSHS domain in type II DNA topoisomerase (From Topology)T: SSHS domain in type II DNA topoisomeraseF: gyrB_1st_3ECOD (1.6)
DDNA_gyraseB_Ce5btcD1 A: a/b three-layered sandwichesX: HAD domain-likeH: HAD domain-relatedT: Toprim domainF: DNA_gyraseB_CECOD (1.6)
ADNA_topoisoIV_1ste5btcA3 A: alpha arraysX: HTHH: HTHT: wingedF: DNA_topoisoIV_1stECOD (1.6)
ADNA_topoisoIV_3rde5btcA2 A: alpha bundlesX: alpha-helical domain in type II DNA topoisomerase (From Topology)H: alpha-helical domain in type II DNA topoisomerase (From Topology)T: alpha-helical domain in type II DNA topoisomeraseF: DNA_topoisoIV_3rdECOD (1.6)
ADNA_topoisoIV_2nd_1e5btcA1 A: a+b two layersX: a+b domain in type II DNA topoisomerase (From Topology)H: a+b domain in type II DNA topoisomerase (From Topology)T: a+b domain in type II DNA topoisomeraseF: DNA_topoisoIV_2nd_1ECOD (1.6)
CDNA_topoisoIV_1ste5btcC1 A: alpha arraysX: HTHH: HTHT: wingedF: DNA_topoisoIV_1stECOD (1.6)
CDNA_topoisoIV_3rde5btcC3 A: alpha bundlesX: alpha-helical domain in type II DNA topoisomerase (From Topology)H: alpha-helical domain in type II DNA topoisomerase (From Topology)T: alpha-helical domain in type II DNA topoisomeraseF: DNA_topoisoIV_3rdECOD (1.6)
CDNA_topoisoIV_2nd_1e5btcC2 A: a+b two layersX: a+b domain in type II DNA topoisomerase (From Topology)H: a+b domain in type II DNA topoisomerase (From Topology)T: a+b domain in type II DNA topoisomeraseF: DNA_topoisoIV_2nd_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
B3.40.50.670 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold CATH (4.3.0)
D3.40.50.670 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
B, D
PF00986DNA gyrase B subunit, carboxyl terminus (DNA_gyraseB_C)DNA gyrase B subunit, carboxyl terminus- Family
B, D
PF01751Toprim domain (Toprim)Toprim domain- Family
A, C
PF00521DNA gyrase/topoisomerase IV, subunit A (DNA_topoisoIV)DNA gyrase/topoisomerase IV, subunit A- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
B, D
DNA gyrase subunit B
E, H
DNA substrate 24-mer GGTCATGAATGACTATGCACGTAA---
F, G
DNA substrate 24-mer TTACGTGCATAGTCATTCATGACC---
A, C
DNA gyrase subunit A

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
B, D
IPR011557DNA gyrase, subunit BFamily
B, D
IPR018522DNA topoisomerase, type IIA, conserved siteConserved Site
B, D
IPR013506DNA topoisomerase, type IIA, subunit B, domain 2Domain
B, D
IPR013760DNA topoisomerase, type IIA-like domain superfamilyHomologous Superfamily
B, D
IPR036890Histidine kinase/HSP90-like ATPase superfamilyHomologous Superfamily
B, D
IPR006171TOPRIM domainDomain
B, D
IPR000565DNA topoisomerase, type IIA, subunit BFamily
B, D
IPR003594Histidine kinase/HSP90-like ATPase domainDomain
B, D
IPR020568Ribosomal protein uS5 domain 2-type superfamilyHomologous Superfamily
B, D
IPR001241DNA topoisomerase, type IIAFamily
B, D
IPR002288DNA gyrase B subunit, C-terminalDomain
B, D
IPR014721Small ribosomal subunit protein uS5 domain 2-type fold, subgroupHomologous Superfamily
B, D
IPR034160DNA gyrase subunit B, TOPRIM domainDomain
B, D
IPR013759DNA topoisomerase, type IIA, subunit B, C-terminalHomologous Superfamily
A, C
IPR035516DNA gyrase/topoisomerase IV, subunit A, C-terminalHomologous Superfamily
A, C
IPR050220Type II DNA TopoisomerasesFamily
A, C
IPR013760DNA topoisomerase, type IIA-like domain superfamilyHomologous Superfamily
A, C
IPR013757DNA topoisomerase, type IIA, alpha-helical domain superfamilyHomologous Superfamily
A, C
IPR013758DNA topoisomerase, type IIA, domain A, alpha-betaHomologous Superfamily
A, C
IPR005743DNA gyrase, subunit AFamily
A, C
IPR006691DNA gyrase/topoisomerase IV, subunit A, C-terminal repeatRepeat
A, C
IPR002205DNA topoisomerase, type IIA, domain ADomain

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
A, C
PTR Parent Component: TYR

RESIDAA0039

PSI-MOD :  O4'-phospho-L-tyrosine MOD:00048