Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth C]Yippee-Mis18_1e4tzcC1 A: beta complex topologyX: ETN0001 domain-like (From Homology)H: ETN0001 domain-likeT: Mss4-likeF: Yippee-Mis18_1ECOD (1.6)
C [auth B]Yippee-Mis18_1e4tzcB1 A: beta complex topologyX: ETN0001 domain-like (From Homology)H: ETN0001 domain-likeT: Mss4-likeF: Yippee-Mis18_1ECOD (1.6)
DYippee-Mis18_1e4tzcD1 A: beta complex topologyX: ETN0001 domain-like (From Homology)H: ETN0001 domain-likeT: Mss4-likeF: Yippee-Mis18_1ECOD (1.6)
B [auth A]Yippee-Mis18_1e4tzcA1 A: beta complex topologyX: ETN0001 domain-like (From Homology)H: ETN0001 domain-likeT: Mss4-likeF: Yippee-Mis18_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth C],
B [auth A],
C [auth B],
D
PF03226Yippee zinc-binding/DNA-binding /Mis18, centromere assembly (Yippee-Mis18)Yippee zinc-binding/DNA-binding /Mis18, centromere assemblyThis family includes both Yippee-type proteins and Mis18 kinetochore proteins. Yippee are putative zinc-binding/DNA-binding proteins. Mis18 are proteins involved in the priming of centromeres for recruiting CENP-A. Mis18-alpha and beta form part of ...This family includes both Yippee-type proteins and Mis18 kinetochore proteins. Yippee are putative zinc-binding/DNA-binding proteins. Mis18 are proteins involved in the priming of centromeres for recruiting CENP-A. Mis18-alpha and beta form part of a small complex with Mis18-binding protein. Mis18-alpha is found to interact with DNA de-methylases through a Leu-rich region located at its carboxyl terminus [5]. This entry also includes the CULT domain proteins such as Cereblon [6].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth C],
B [auth A],
C [auth B],
D
Protein cereblon