4R5M
Crystal structure of Vc-Aspartate beta-semialdehyde-dehydrogenase with NADP and 4-Nitro-2-Phosphono-Benzoic acid
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | Semialdhyde_dhC | e4r5mB2 | A: a+b two layers | X: FwdE/GAPDH domain-like | H: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology) | T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | F: Semialdhyde_dhC | ECOD (1.6) |
B | Semialdhyde_dh | e4r5mB1 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: NAD(P)-binding Rossmann-fold domains | F: Semialdhyde_dh | ECOD (1.6) |
A | Semialdhyde_dhC | e4r5mA2 | A: a+b two layers | X: FwdE/GAPDH domain-like | H: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology) | T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | F: Semialdhyde_dhC | ECOD (1.6) |
A | Semialdhyde_dh | e4r5mA1 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: NAD(P)-binding Rossmann-fold domains | F: Semialdhyde_dh | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 3.40.50.720 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | NAD(P)-binding Rossmann-like Domain | CATH (4.3.0) |
B | 3.30.360.10 | Alpha Beta | 2-Layer Sandwich | Dihydrodipicolinate Reductase | domain 2 | CATH (4.3.0) |
A | 3.40.50.720 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | NAD(P)-binding Rossmann-like Domain | CATH (4.3.0) |
A | 3.30.360.10 | Alpha Beta | 2-Layer Sandwich | Dihydrodipicolinate Reductase | domain 2 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF01118 | Semialdehyde dehydrogenase, NAD binding domain (Semialdhyde_dh) | Semialdehyde dehydrogenase, NAD binding domain | This Pfam entry contains the following members: N-acetyl-glutamine semialdehyde dehydrogenase (AgrC) Aspartate-semialdehyde dehydrogenase | Domain | |
PF02774 | Semialdehyde dehydrogenase, dimerisation domain (Semialdhyde_dhC) | Semialdehyde dehydrogenase, dimerisation domain | This Pfam entry contains the following members: N-acetyl-glutamine semialdehyde dehydrogenase (AgrC) Aspartate-semialdehyde dehydrogenase. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR012080 | Aspartate-semialdehyde dehydrogenase | Family | |
IPR012280 | Semialdehyde dehydrogenase, dimerisation domain | Domain | |
IPR036291 | NAD(P)-binding domain superfamily | Homologous Superfamily | |
IPR011534 | Aspartate-semialdehyde dehydrogenase, gamma-type | Family | |
IPR000319 | Aspartate-semialdehyde dehydrogenase, conserved site | Conserved Site | |
IPR000534 | Semialdehyde dehydrogenase, NAD-binding | Domain |