4MVJ

2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3-phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate.


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AGp_dh_Ce4mvjA2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
AGp_dh_N_2e4mvjA1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
BGp_dh_Ce4mvjB2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
BGp_dh_N_2e4mvjB1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
CGp_dh_Ce4mvjC2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
CGp_dh_N_2e4mvjC1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
KGp_dh_Ce4mvjK2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
KGp_dh_N_2e4mvjK1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
NGp_dh_Ce4mvjN2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
NGp_dh_N_2e4mvjN1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
DGp_dh_Ce4mvjD2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
DGp_dh_N_2e4mvjD1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
LGp_dh_Ce4mvjL2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
LGp_dh_N_2e4mvjL1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
EGp_dh_Ce4mvjE2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
EGp_dh_N_2e4mvjE1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
GGp_dh_Ce4mvjG2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
GGp_dh_N_2e4mvjG1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
HGp_dh_Ce4mvjH2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
HGp_dh_N_2e4mvjH1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
IGp_dh_Ce4mvjI2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
IGp_dh_N_2e4mvjI1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
MGp_dh_Ce4mvjM2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
MGp_dh_N_2e4mvjM1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
PGp_dh_Ce4mvjP2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
PGp_dh_N_2e4mvjP1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
FGp_dh_Ce4mvjF2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
FGp_dh_N_2e4mvjF1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
JGp_dh_Ce4mvjJ2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
JGp_dh_N_2e4mvjJ1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
OGp_dh_Ce4mvjO2 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
OGp_dh_N_2e4mvjO1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
A3.30.360.10 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase domain 2CATH (4.3.0)
B3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
B3.30.360.10 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase domain 2CATH (4.3.0)
C3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
C3.30.360.10 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase domain 2CATH (4.3.0)
K3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
K3.30.360.10 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase domain 2CATH (4.3.0)
N3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
N3.30.360.10 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase domain 2CATH (4.3.0)
D3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
D3.30.360.10 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase domain 2CATH (4.3.0)
L3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
L3.30.360.10 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase domain 2CATH (4.3.0)
E3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
E3.30.360.10 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase domain 2CATH (4.3.0)
G3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
G3.30.360.10 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase domain 2CATH (4.3.0)
H3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
H3.30.360.10 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase domain 2CATH (4.3.0)
I3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
I3.30.360.10 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase domain 2CATH (4.3.0)
M3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
M3.30.360.10 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase domain 2CATH (4.3.0)
P3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
P3.30.360.10 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase domain 2CATH (4.3.0)
F3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
F3.30.360.10 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase domain 2CATH (4.3.0)
J3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
J3.30.360.10 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase domain 2CATH (4.3.0)
O3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
O3.30.360.10 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase domain 2CATH (4.3.0)

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
A, B, C, K, N
ALY Parent Component: LYS

RESIDAA0055

PSI-MOD :  N6-acetyl-L-lysine MOD:00064
ALY Parent Component: LYS

RESIDAA0055 , AA0055

PSI-MOD :  N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064
ALY Parent Component: LYS

RESIDAA0055 , AA0055 , AA0055

PSI-MOD :  N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064
SCY Parent Component: CYS

RESIDAA0055 , AA0055 , AA0055 , AA0056

PSI-MOD :  N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , S-acetyl-L-cysteine MOD:00065
ALY Parent Component: LYS

RESIDAA0055 , AA0055 , AA0055 , AA0056 , AA0055

PSI-MOD :  N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , S-acetyl-L-cysteine MOD:00065 , N6-acetyl-L-lysine MOD:00064
SCY Parent Component: CYS

RESIDAA0055 , AA0055 , AA0055 , AA0056 , AA0055 , AA0056

PSI-MOD :  N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , S-acetyl-L-cysteine MOD:00065 , N6-acetyl-L-lysine MOD:00064 , S-acetyl-L-cysteine MOD:00065
ALY Parent Component: LYS

RESIDAA0055 , AA0055 , AA0055 , AA0056 , AA0055 , AA0056 , AA0055

PSI-MOD :  N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , S-acetyl-L-cysteine MOD:00065 , N6-acetyl-L-lysine MOD:00064 , S-acetyl-L-cysteine MOD:00065 , N6-acetyl-L-lysine MOD:00064
ALY Parent Component: LYS

RESIDAA0055 , AA0055 , AA0055 , AA0056 , AA0055 , AA0056 , AA0055 , AA0055

PSI-MOD :  N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , S-acetyl-L-cysteine MOD:00065 , N6-acetyl-L-lysine MOD:00064 , S-acetyl-L-cysteine MOD:00065 , N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064
ALY Parent Component: LYS

RESIDAA0055 , AA0055 , AA0055 , AA0056 , AA0055 , AA0056 , AA0055 , AA0055 , AA0055

PSI-MOD :  N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , S-acetyl-L-cysteine MOD:00065 , N6-acetyl-L-lysine MOD:00064 , S-acetyl-L-cysteine MOD:00065 , N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064
SCY Parent Component: CYS

RESIDAA0055 , AA0055 , AA0055 , AA0056 , AA0055 , AA0056 , AA0055 , AA0055 , AA0055 , AA0056

PSI-MOD :  N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , S-acetyl-L-cysteine MOD:00065 , N6-acetyl-L-lysine MOD:00064 , S-acetyl-L-cysteine MOD:00065 , N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , S-acetyl-L-cysteine MOD:00065
F, J, O
ALY Parent Component: LYS

RESIDAA0055 , AA0055 , AA0055 , AA0056 , AA0055 , AA0056 , AA0055 , AA0055 , AA0055 , AA0056 , AA0055

PSI-MOD :  N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , S-acetyl-L-cysteine MOD:00065 , N6-acetyl-L-lysine MOD:00064 , S-acetyl-L-cysteine MOD:00065 , N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , N6-acetyl-L-lysine MOD:00064 , S-acetyl-L-cysteine MOD:00065 , N6-acetyl-L-lysine MOD:00064