4KY0

Crystal structure of a substrate-free glutamate transporter homologue from Thermococcus kodakarensis

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD
Membrane Protein Annotation: mpstruc

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4ky0a_	Membrane and cell surface proteins and peptides	Proton glutamate symport protein	Proton glutamate symport protein	Proton glutamate symport protein	automated matches	(Thermococcus kodakarensis KOD1 ) [TaxId: 69014 ],	SCOPe (2.08)
C	d4ky0c1	Membrane and cell surface proteins and peptides	Proton glutamate symport protein	Proton glutamate symport protein	Proton glutamate symport protein	automated matches	(Thermococcus kodakarensis KOD1 ) [TaxId: 69014 ],	SCOPe (2.08)
C	d4ky0c2	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Thermococcus kodakarensis KOD1 ) [TaxId: 69014 ],	SCOPe (2.08)
B	d4ky0b_	Membrane and cell surface proteins and peptides	Proton glutamate symport protein	Proton glutamate symport protein	Proton glutamate symport protein	automated matches	(Thermococcus kodakarensis KOD1 ) [TaxId: 69014 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Proton glutamate symport protein	8065925	3001772	SCOP2B (2022-06-29)
C	SCOP2 Family	Proton glutamate symport protein	8065924	4003905	SCOP2 (2022-06-29)
C	SCOP2 Superfamily	Proton glutamate symport protein	8065925	3001772	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Proton glutamate symport protein	8065925	3001772	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	SDF	e4ky0A1	A: alpha complex topology	X: Proton glutamate symport protein (From Topology)	H: Proton glutamate symport protein (From Topology)	T: Proton glutamate symport protein	F: SDF	ECOD (1.6)
C	SDF	e4ky0C1	A: alpha complex topology	X: Proton glutamate symport protein (From Topology)	H: Proton glutamate symport protein (From Topology)	T: Proton glutamate symport protein	F: SDF	ECOD (1.6)
B	SDF	e4ky0B1	A: alpha complex topology	X: Proton glutamate symport protein (From Topology)	H: Proton glutamate symport protein (From Topology)	T: Proton glutamate symport protein	F: SDF	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.3860.10	Mainly Alpha	Orthogonal Bundle	Proton glutamate symport protein	Sodium:dicarboxylate symporter	CATH (4.3.0)
C	1.10.3860.10	Mainly Alpha	Orthogonal Bundle	Proton glutamate symport protein	Sodium:dicarboxylate symporter	CATH (4.3.0)
B	1.10.3860.10	Mainly Alpha	Orthogonal Bundle	Proton glutamate symport protein	Sodium:dicarboxylate symporter	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF00375	Sodium:dicarboxylate symporter family (SDF)	Sodium:dicarboxylate symporter family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	Proton/glutamate symporter, SDF family	active transmembrane transporter activity transporter activity symporter activity transmembrane transporter activity secondary active transmembrane transporter activity	organic acid transport localization organic anion transport carboxylic acid transport transport establishment of localization	cellular anatomical structure membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR001991	Sodium:dicarboxylate symporter	Family
A, B, C	IPR036458	Sodium:dicarboxylate symporter superfamily	Homologous Superfamily
A, B, C	IPR018107	Sodium:dicarboxylate symporter, conserved site	Conserved Site

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A, B, C	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A, B, C	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A, B, C	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	Amino Acid Secondary Transporters	Aspartate Transporter, substrate-free

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.