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Data API
4KS5
Influenza neuraminidase in complex with antiviral compound (3S,4R,5R)-4-(acetylamino)-3-[4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl]-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Domain Annotation: SCOP/SCOPe Classification
SCOP-e Database Homepage
Chains
Domain Info
Class
Fold
Superfamily
Family
Domain
Species
Provenance Source (Version)
A
d4ks5a_
All beta proteins
6-bladed beta-propeller
Sialidases
automated matches
automated matches
Influenza Virus
(
Influenza A virus (A/duck/Ukraine/1/1963(H3N8))
) [TaxId:
385580
],
SCOPe (2.08)
Domain Annotation: SCOP2 Classification
SCOP2 Database Homepage
Chains
Type
Family Name
Domain Identifier
Family Identifier
Provenance Source (Version)
A
SCOP2B Superfamily
Sialidases
8071700
3001607
SCOP2B (2022-06-29)
Domain Annotation: ECOD Classification
ECOD Database Homepage
Chains
Family Name
Domain Identifier
Architecture
Possible Homology
Homology
Topology
Family
Provenance Source (Version)
A
Neur
e4ks5A1
A: beta duplicates or obligate multimers
X: beta-propeller-like
H: beta-propeller
T: 6-bladed
F: Neur
ECOD (1.6)
Domain Annotation: CATH
CATH Database Homepage
Chain
Domain
Class
Architecture
Topology
Homology
Provenance Source (Version)
A
2.120.10.10
Mainly Beta
6 Propeller
Neuraminidase
CATH (4.3.0)
Protein Family Annotation
Pfam Database Homepage
Chains
Accession
Name
Description
Comments
Source
A
PF00064
Neuraminidase (Neur)
Neuraminidase
-
Repeat
Gene Ontology: Gene Product Annotation
Gene Ontology Database Homepage
Chains
Polymer
Molecular Function
Biological Process
Cellular Component
A
Neuraminidase
cation binding
ion binding
binding
metal ion binding
small molecule binding
carbohydrate metabolic process
primary metabolic process
metabolic process
cellular process
biological process involved in interspecies interaction between organisms
non-lytic viral release
viral budding
viral life cycle
biological process involved in interaction with host
biological process involved in symbiotic interaction
virion assembly
exit from host cell
viral process
viral budding from plasma membrane
carbohydrate metabolic process
primary metabolic process
metabolic process
cellular process
biological process involved in interspecies interaction between organisms
non-lytic viral release
viral budding
viral life cycle
biological process involved in interaction with host
biological process involved in symbiotic interaction
virion assembly
exit from host cell
viral process
viral budding from plasma membrane
viral release from host cell
Less
cellular anatomical structure
membrane
host cell plasma membrane
host cellular component
host cell part
host cell membrane
virion component
virion membrane
InterPro: Protein Family Classification
InterPro Database Homepage
Chains
Accession
Name
Type
A
IPR001860
Glycoside hydrolase, family 34
Family
A
IPR036278
Sialidase superfamily
Homologous Superfamily
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