3E3I

H. influenzae beta-carbonic anhydrase, variant G41A with 100 mM bicarbonate

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
J	d3e3ij_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Haemophilus influenzae ) [TaxId: 727 ],	SCOPe (2.08)
A	d3e3ia_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Haemophilus influenzae ) [TaxId: 727 ],	SCOPe (2.08)
B	d3e3ib_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Haemophilus influenzae ) [TaxId: 727 ],	SCOPe (2.08)
C	d3e3ic_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Haemophilus influenzae ) [TaxId: 727 ],	SCOPe (2.08)
D	d3e3id_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Haemophilus influenzae ) [TaxId: 727 ],	SCOPe (2.08)
E	d3e3ie_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Haemophilus influenzae ) [TaxId: 727 ],	SCOPe (2.08)
F	d3e3if_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Haemophilus influenzae ) [TaxId: 727 ],	SCOPe (2.08)
G	d3e3ig_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Haemophilus influenzae ) [TaxId: 727 ],	SCOPe (2.08)
H	d3e3ih_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Haemophilus influenzae ) [TaxId: 727 ],	SCOPe (2.08)
I	d3e3ii_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Haemophilus influenzae ) [TaxId: 727 ],	SCOPe (2.08)
K	d3e3ik_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Haemophilus influenzae ) [TaxId: 727 ],	SCOPe (2.08)
L	d3e3il_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Haemophilus influenzae ) [TaxId: 727 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
J	SCOP2B Superfamily	beta-carbonic anhydrase, cab	8082595	3000468	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	beta-carbonic anhydrase, cab	8082595	3000468	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	beta-carbonic anhydrase, cab	8082595	3000468	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	beta-carbonic anhydrase, cab	8082595	3000468	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	beta-carbonic anhydrase, cab	8082595	3000468	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	beta-carbonic anhydrase, cab	8082595	3000468	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	beta-carbonic anhydrase, cab	8082595	3000468	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	beta-carbonic anhydrase, cab	8082595	3000468	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	beta-carbonic anhydrase, cab	8082595	3000468	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	beta-carbonic anhydrase, cab	8082595	3000468	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	beta-carbonic anhydrase, cab	8082595	3000468	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	beta-carbonic anhydrase, cab	8082595	3000468	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
J	Pro_CA	e3e3iJ1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: Pro_CA	ECOD (1.6)
A	Pro_CA	e3e3iA1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: Pro_CA	ECOD (1.6)
B	Pro_CA	e3e3iB1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: Pro_CA	ECOD (1.6)
C	Pro_CA	e3e3iC1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: Pro_CA	ECOD (1.6)
D	Pro_CA	e3e3iD1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: Pro_CA	ECOD (1.6)
E	Pro_CA	e3e3iE1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: Pro_CA	ECOD (1.6)
F	Pro_CA	e3e3iF1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: Pro_CA	ECOD (1.6)
G	Pro_CA	e3e3iG1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: Pro_CA	ECOD (1.6)
H	Pro_CA	e3e3iH1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: Pro_CA	ECOD (1.6)
I	Pro_CA	e3e3iI1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: Pro_CA	ECOD (1.6)
K	Pro_CA	e3e3iK1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: Pro_CA	ECOD (1.6)
L	Pro_CA	e3e3iL1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: Pro_CA	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
J	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
A	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
B	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
C	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
D	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
E	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
F	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
G	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
H	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
I	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
K	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
L	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	PF00484	Carbonic anhydrase (Pro_CA)	Carbonic anhydrase	This family includes carbonic anhydrases as well as a family of non-functional homologues related to YbcF.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	Carbonic anhydrase 2	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding carbonate dehydratase activity hydro-lyase activity lyase activity catalytic activity carbon-oxygen lyase activity	carbon utilization response to nutrient levels response to stimulus	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR001765	Carbonic anhydrase	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR015892	Carbonic anhydrase, prokaryotic-like, conserved site	Conserved Site
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR036874	Carbonic anhydrase superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.