Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad2vyva1 Alpha and beta proteins (a/b) NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (Escherichia coli BL21(DE3) ) [TaxId: 469008 ], SCOPe (2.08)
Ad2vyva2 Alpha and beta proteins (a+b) FwdE/GAPDH domain-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain GAPDH-like Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (Escherichia coli BL21(DE3) ) [TaxId: 469008 ], SCOPe (2.08)
Bd2vyvb1 Alpha and beta proteins (a/b) NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (Escherichia coli BL21(DE3) ) [TaxId: 469008 ], SCOPe (2.08)
Bd2vyvb2 Alpha and beta proteins (a+b) FwdE/GAPDH domain-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain GAPDH-like Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (Escherichia coli BL21(DE3) ) [TaxId: 469008 ], SCOPe (2.08)
Cd2vyvc1 Alpha and beta proteins (a/b) NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (Escherichia coli BL21(DE3) ) [TaxId: 469008 ], SCOPe (2.08)
Cd2vyvc2 Alpha and beta proteins (a+b) FwdE/GAPDH domain-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain GAPDH-like Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (Escherichia coli BL21(DE3) ) [TaxId: 469008 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
DSCOP2B SuperfamilyGAPDH-like 8068867 3000043 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyGAPDH-like 8000884 3000043 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyGAPDH-like 8000884 3000043 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyGAPDH-like 8000884 3000043 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
DGp_dh_Ce2vyvD1 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
DGp_dh_N_2e2vyvD2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
AGp_dh_Ce2vyvA1 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
AGp_dh_N_2e2vyvA2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
BGp_dh_Ce2vyvB1 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
BGp_dh_N_2e2vyvB2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)
CGp_dh_Ce2vyvC1 A: a+b two layersX: FwdE/GAPDH domain-likeH: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (From Topology)T: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domainF: Gp_dh_CECOD (1.6)
CGp_dh_N_2e2vyvC2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: Gp_dh_N_2ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF02800Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain (Gp_dh_C)Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domainGAPDH is a tetrameric NAD-binding enzyme involved in glycolysis and glyconeogenesis. C-terminal domain is a mixed alpha/antiparallel beta fold.Domain
PF00044Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain (Gp_dh_N)Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domainGAPDH is a tetrameric NAD-binding enzyme involved in glycolysis and glyconeogenesis. N-terminal domain is a Rossmann NAD(P) binding fold.Domain
A, B, C
PF02800Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain (Gp_dh_C)Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domainGAPDH is a tetrameric NAD-binding enzyme involved in glycolysis and glyconeogenesis. C-terminal domain is a mixed alpha/antiparallel beta fold.Domain
A, B, C
PF00044Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain (Gp_dh_N)Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domainGAPDH is a tetrameric NAD-binding enzyme involved in glycolysis and glyconeogenesis. N-terminal domain is a Rossmann NAD(P) binding fold.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE
A, B, C
GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
CSD Parent Component: CYS

RESIDAA0262

PSI-MOD :  L-cysteine sulfinic acid MOD:00267
CSX Parent Component: CYS

RESIDAA0262 , AA0451

PSI-MOD :  L-cysteine sulfinic acid MOD:00267 , 2'-(S-L-cysteinyl)-6'-hydroxy-L-tryptophan sulfoxide MOD:01380
A, B, C
CSD Parent Component: CYS

RESIDAA0262 , AA0451 , AA0262

PSI-MOD :  L-cysteine sulfinic acid MOD:00267 , 2'-(S-L-cysteinyl)-6'-hydroxy-L-tryptophan sulfoxide MOD:01380 , L-cysteine sulfinic acid MOD:00267