1NCC
CRYSTAL STRUCTURES OF TWO MUTANT NEURAMINIDASE-ANTIBODY COMPLEXES WITH AMINO ACID SUBSTITUTIONS IN THE INTERFACE
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A [auth N] | SCOP2B Superfamily | Sialidases | 8032977 | 3001607 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B [auth L] | C1-set_4 | e1nccL2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: C1-set_4 | ECOD (1.6) |
B [auth L] | V-set | e1nccL1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set | ECOD (1.6) |
C [auth H] | V-set_8 | e1nccH1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_8 | ECOD (1.6) |
C [auth H] | C1-set_1 | e1nccH2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: C1-set_1 | ECOD (1.6) |
A [auth N] | Neur | e1nccN1 | A: beta duplicates or obligate multimers | X: beta-propeller-like | H: beta-propeller | T: 6-bladed | F: Neur | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B [auth L] | 2.60.40.10 | Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulins | CATH (4.3.0) |
C [auth H] | 2.60.40.10 | Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulins | CATH (4.3.0) |
A [auth N] | 2.120.10.10 | Mainly Beta | 6 Propeller | Neuraminidase | CATH (4.3.0) |
IMGT Antibody Annotation IMGT Database Homepage
Chain | Protein Name | Description | Organism Name | Gene Allele Name(s) | Domain Name(s) | Receptor Type | Receptor Description | Provenance Source |
---|---|---|---|---|---|---|---|---|
B [auth L] | NC41 | L-KAPPA | Mus musculus (house mouse) | IGKV6-25*01, IGKJ1*01, IGKJ1*02, IGKC*01, IGKC*02 | V-DOMAIN V-KAPPA, C-DOMAIN C-KAPPA | IG | FAB-GAMMA-2A_KAPPA | IMGT (202447-0) |
C [auth H] | NC41 | VH-CH1 | Mus musculus (house mouse) | IGHV9-3*03, IGHV9-3*02, IGHJ2*01, IGHJ4*01, IGHG2A*01, IGHG2A*02 | V-DOMAIN VH, C-DOMAIN CH1 | IG | FAB-GAMMA-2A_KAPPA | IMGT (202447-0) |
SAbDab Antibody Annotation SAbDab Database Homepage
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
---|---|---|---|---|---|
B [auth L] | Light Chain | IGKV6 | Kappa | influenza a subtype n9 neuraminidase | SAbDab (2024-11-29) |
C [auth H] | Heavy Chain | IGHV9 | - | influenza a subtype n9 neuraminidase | SAbDab (2024-11-29) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
C [auth H] | PF07654 | Immunoglobulin C1-set domain (C1-set) | Immunoglobulin C1-set domain | - | Domain |
A [auth N] | PF00064 | Neuraminidase (Neur) | Neuraminidase | - | Repeat |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
C [auth H] | IPR036179 | Immunoglobulin-like domain superfamily | Homologous Superfamily |
C [auth H] | IPR003597 | Immunoglobulin C1-set | Domain |
C [auth H] | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site | Conserved Site |
C [auth H] | IPR050380 | Immune Recognition and Response Modulators | Family |
C [auth H] | IPR013783 | Immunoglobulin-like fold | Homologous Superfamily |
C [auth H] | IPR007110 | Immunoglobulin-like domain | Domain |
A [auth N] | IPR001860 | Glycoside hydrolase, family 34 | Family |
A [auth N] | IPR033654 | Sialidase, Influenza viruses A/B | Domain |
A [auth N] | IPR036278 | Sialidase superfamily | Homologous Superfamily |