1A2P

BARNASE WILDTYPE STRUCTURE AT 1.5 ANGSTROMS RESOLUTION

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1a2pa_	Alpha and beta proteins (a+b)	Microbial ribonucleases	Microbial ribonucleases	Bacterial ribonucleases	Barnase	(Bacillus amyloliquefaciens ) [TaxId: 1390 ],	SCOPe (2.08)
B	d1a2pb_	Alpha and beta proteins (a+b)	Microbial ribonucleases	Microbial ribonucleases	Bacterial ribonucleases	Barnase	(Bacillus amyloliquefaciens ) [TaxId: 1390 ],	SCOPe (2.08)
C	d1a2pc_	Alpha and beta proteins (a+b)	Microbial ribonucleases	Microbial ribonucleases	Bacterial ribonucleases	Barnase	(Bacillus amyloliquefaciens ) [TaxId: 1390 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Bacterial ribonucleases	8021174	4001841	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Microbial ribonucleases	8033554	3001847	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Microbial ribonucleases	8033554	3001847	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Microbial ribonucleases	8033554	3001847	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Ribonuclease	e1a2pA1	A: a+b two layers	X: Microbial ribonucleases-like	H: Microbial ribonucleases (From Topology)	T: Microbial ribonucleases	F: Ribonuclease	ECOD (1.6)
B	Ribonuclease	e1a2pB1	A: a+b two layers	X: Microbial ribonucleases-like	H: Microbial ribonucleases (From Topology)	T: Microbial ribonucleases	F: Ribonuclease	ECOD (1.6)
C	Ribonuclease	e1a2pC1	A: a+b two layers	X: Microbial ribonucleases-like	H: Microbial ribonucleases (From Topology)	T: Microbial ribonucleases	F: Ribonuclease	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.10.450.30	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
B	3.10.450.30	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
C	3.10.450.30	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF00545	ribonuclease (Ribonuclease)	ribonuclease	This enzyme hydrolyses RNA and oligoribonucleotides.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	BARNASE	endonuclease activity nuclease activity hydrolase activity, acting on ester bonds catalytic activity, acting on RNA RNA endonuclease activity catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity catalytic activity RNA binding binding organic cyclic compound binding nucleic acid binding	-	cellular anatomical structure extracellular region

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR000026	Guanine-specific ribonuclease N1-like	Family
A, B, C	IPR053753	Ribonuclease N1/T1-like	Homologous Superfamily
A, B, C	IPR001887	Barnase	Family
A, B, C	IPR016191	Ribonuclease/ribotoxin	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.