3D View: 7AAG

Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-617

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RCSB PDB Mol* Viewer 2.10.6 [10/28/2024, 3:56:31 PM]
Sequence of
     ​G​​S​​H​​M​​I​​P​​R​​F​​G​​V​85   ​K​​T​​E​​Q​​E​​D​​V​​L​​A​​K​95   ​E​​L​​E​​D​​V​​N​​K​​W​​G​​L​105  ​H​​V​​F​​R​​I​​A​​E​​L​​S​​G​115  ​N​​R​​P​​L​​T​​V​​I​​M​​H​​T​125  ​I​​F​​Q​​E​​R​​D​​L​​L​​K​​T​135  ​F​​K​​I​​P​​V​​D​​T​​L​​I​​T​145  ​Y​​L​​M​​T​​L​​E​​D​​H​​Y​​H​155  ​A​​D​​V​​A​​Y​​H​​N​​N​​I​​H​165  ​A​​A​​D​​V​​V​​Q​​S​​T​​H​​V​175  ​L​​L​​S​​T​​P​​A​​L​​E​​A​​V​185  ​F​​T​​D​​L​​E​​I​​L​​A​​A​​I​195  ​F​​A​​S​​A​​I​​H​​D​​V​​D​​H​205  ​P​​G​​V​​S​​N​​Q​​F​​L​​I​​N​215  ​T​​N​​S​​E​​L​​A​​L​​M​​Y​​N​225  ​D​​S​​S​​V​​L​​E​​N​​H​​H​​L​235  ​A​​V​​G​​F​​K​​L​​L​​Q​​E​​E​245  ​N​​C​​D​​I​​F​​Q​​N​​L​​T​​K​255  ​K​​Q​​R​​Q​​S​​L​​R​​K​​M​​V​265  ​I​​D​​I​​V​​L​​A​​T​​D​​M​​S​275  ​K​​H​​M​​N​​L​​L​​A​​D​​L​​K​285  ​T​​M​​V​​E​​T​​K​​K​​V​​T​​S​295  ​S​​G​​V​​L​​L​​L​​D​​N​​Y​​S​305  ​D​​R​​I​​Q​​V​​L​​Q​​N​​M​​V​315  ​H​​C​​A​​D​​L​​S​​N​​P​​T​​K​325  ​P​​L​​Q​​L​​Y​​R​​Q​​W​​T​​D​335  ​R​​I​​M​​E​​E​​F​​F​​R​​Q​​G​345  ​D​​R​​E​​R​​E​​R​​G​​M​​E​​I​355  ​S​​P​​M​​C​​D​​K​​H​​N​​A​​S​365  ​V​​E​​K​​S​​Q​​V​​G​​F​​I​​D​375  ​Y​​I​​V​​H​​P​​L​​W​​E​​T​​W​385  ​A​​D​​L​​V​​H​​P​​D​​A​​Q​​D​395  ​I​​L​​D​​T​​L​​E​​D​​N​​R​​E​405  ​W​​Y​​Q​​S​​T​​I​​P​​Q​​S​​P​     ​S​​P​​A​​P​​D​​D​​P​​E​​E​​G​     ​R​​Q​​G​​Q​​T​​E​​K​​F​​Q​​F​     ​E​​L​​T​​L​

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